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Idiosyncratic Adverse Reactions to Antiepileptic Drugs
Summary: Idiosyncratic drug reactions may be defined as adverse effects that cannot be explained by the known mechanisms of action of the offending agent, do not occur at any dose in most patients,… Expand
Modulation of interhemispheric inhibition by volitional motor activity: an ipsilateral silent period study
- F. Giovannelli, A. Borgheresi, +4 authors U. Ziemann
- Psychology, Medicine
- The Journal of physiology
- 1 November 2009
Brief interruption of voluntary EMG in a hand muscle by focal transcranial magnetic stimulation (TMS) of the ipsilateral primary motor cortex (M1), the so‐called ipsilateral silent period (ISP), is a… Expand
Transcranial magnetic stimulation and epilepsy
- C. Tassinari, M. Cincotta, G. Zaccara, R. Michelucci
- Psychology, Medicine
- Clinical Neurophysiology
- 1 May 2003
Epileptic conditions are characterized by an altered balance between excitatory and inhibitory influences at the cortical level. Transcranial magnetic stimulation (TMS) provides a noninvasive… Expand
Clinical Pharmacokinetics of Valproic Acid — 1988
SummarySodium valproate (valproic acid) has been widely used in the last decade and is now considered a relatively safe and effective anticonvulsant agent. Recently, several investigators have… Expand
Incidence and predictors of acute symptomatic seizures after stroke
Objective: To assess incidence and predictors of acute symptomatic seizures in a prospective cohort of patients with first stroke. Methods: Patients with first stroke hospitalized in 31 Italian… Expand
Slow Repetitive TMS for Drug‐resistant Epilepsy: Clinical and EEG Findings of a Placebo‐controlled Trial
Summary: Purpose: To assess the effectiveness of slow repetitive transcranial magnetic stimulation (rTMS) as an adjunctive treatment for drug‐resistant epilepsy.
Recommendations of the Italian League Against Epilepsy Working Group on Generic Products of Antiepileptic Drugs
- E. Perucca, F. Albani, G. Capovilla, B. Bernardina, R. Michelucci, G. Zaccara
- 1 December 2006
Summary: The availability of generic products of antiepileptic drugs (AEDs) has been increasing in recent years. In view of the importance of the issue, the Italian League against Epilepsy (LICE)… Expand
Novel treatment options for epilepsy: focus on perampanel.
Perampanel is a new chemical entity recently approved in the United States (US) and European Union (EU) as adjunctive treatment of partial-onset seizures with and without secondary generalization in… Expand
Neurological adverse events of new generation sodium blocker antiepileptic drugs. Meta-analysis of randomized, double-blinded studies with eslicarbazepine acetate, lacosamide and oxcarbazepine
PURPOSE Analysis of overall tolerability and neurological adverse effects (AEs) of eslicarbazepine acetate (ESL), lacosamide (LCM) and oxcarbazepine (OXC) from double-blind, placebo-controlled… Expand
Comparison of the efficacy and tolerability of new antiepileptic drugs: what can we learn from long‐term studies?
- G. Zaccara, A. Messori, M. Cincotta, G. Burchini
- Acta neurologica Scandinavica
- 1 September 2006
Objective – A review of long‐term open‐label studies was performed with the aim of detecting differences in efficacy and/or tolerability of new antiepileptic drugs (AEDs).