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Continuous association of cadherin with β-catenin requires the non-receptor tyrosine-kinase Fer
The function of Type 1, classic cadherins depends on their association with the actin cytoskeleton, a connection mediated by α- and β-catenin. The phosphorylation state of β-catenin is crucial for… Expand
Chern semimetal and the quantized anomalous Hall effect in HgCr2Se4.
In 3D momentum space, a topological phase boundary separating the Chern insulating layers from normal insulating layers may exist, where the gap must be closed, resulting in a "Chern semimetal" state… Expand
Cloning, expression, and initial characterization of a novel cytokine-like gene family.
We report the identification and characterization of a novel cytokine-like gene family using structure-based methods to search for novel four-helix-bundle cytokines in genomics databases. There are… Expand
Neuron deficit in the white matter and subplate in periventricular leukomalacia
The cellular basis of cognitive abnormalities in preterm infants with periventricular leukomalacia (PVL) is uncertain. One important possibility is that damage to white matter and subplate neurons… Expand
Downregulation of GLP-1 and GIP Receptor Expression by Hyperglycemia
Stimulation of insulin secretion by the incretin hormones glucagon-like peptide 1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP) has been found to be diminished in type 2 diabetes. We… Expand
Long-Term Exposure to Air Pollution and Increased Risk of Membranous Nephropathy in China.
- X. Xu, Guobao Wang, +10 authors F. Hou
- Journal of the American Society of Nephrology…
- 30 June 2016
The effect of air pollution on the changing pattern of glomerulopathy has not been studied. We estimated the profile of and temporal change in glomerular diseases in an 11-year renal biopsy series… Expand
Epidemiology and Clinical Correlates of AKI in Chinese Hospitalized Adults.
- X. Xu, S. Nie, +9 authors F. Hou
- Clinical journal of the American Society of…
- 4 September 2015
BACKGROUND AND OBJECTIVES Comprehensive epidemiologic data on AKI are particularly lacking in Asian countries. This study sought to assess the epidemiology and clinical correlates of AKI among… Expand
Dipeptidyl Peptidase 4 Inhibitor Sitagliptin Protects Endothelial Function in Hypertension Through a Glucagon–Like Peptide 1–Dependent Mechanism
Sitagliptin, a selective dipeptidyl peptidase 4 inhibitor, inhibits the inactivation and degradation of glucagon like peptide 1 (GLP-1), which is used for the treatment of type 2 diabetes mellitus.… Expand
Chitosan oligosaccharides attenuate hydrogen peroxide-induced stress injury in human umbilical vein endothelial cells.
Chitosan oligosaccharides (COS) have been reported to have anticancer activity, immuno-enhancing effect and antimicrobial activity. However, other biological activities are unknown. Herein, we… Expand
Mutations in the cytoplasmic domain of P0 reveal a role for PKC-mediated phosphorylation in adhesion and myelination
Mutations in P0 (MPZ), the major myelin protein of the peripheral nervous system, cause the inherited demyelinating neuropathy Charcot-Marie-Tooth disease type 1B. P0 is a member of the… Expand