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A model for the role of multiple cysteine residues involved in ribonucleotide reduction: amazing and still confusing.
Ribonucleotide reductase from Escherichia coli catalyzes the conversion of nucleotides to deoxynucleotides. Multiple cysteins have been postulated to play a key role in this process. To test the roleExpand
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Characterization of C439SR1, a mutant of Escherichia coli ribonucleotide diphosphate reductase: evidence that C439 is a residue essential for nucleotide reduction and C439SR1 is a protein possessing
Ribonucleotide reductase from Escherichia coli catalyzes the conversion of nucleotides to deoxynucleotides. Cysteine 439 is proposed to be the protein radical on R1 which initiates the reductionExpand
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Interaction of C225SR1 mutant subunit of ribonucleotide reductase with R2 and nucleoside diphosphates: tales of a suicidal enzyme.
Ribonucleotide reductase (RDPR) from Escherichia coli is composed of two subunits, R1 and R2, both of which are required to catalyze the conversion of nucleotides to deoxynucleotides. This reductionExpand
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Propofol inhibits pressure-stimulated macrophage phagocytosis via the GABAA receptor and dysregulation of p130cas phosphorylation.
Surgical stress and anesthesia result in systemic immunosuppression. Propofol, a commonly used anesthetic agent, alters immune cell functions. Previously, we demonstrated that extracellular pressureExpand
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Ribonucleotide reductases: radical enzymes with suicidal tendencies.
Ribonucleotide reductases isolated from E. coli and from L. leichmannii differ considerably in their primary and quaternary structures, as well as in their cofactor requirements. Despite theseExpand
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[Patient-controlled analgesia with lornoxicam in patients undergoing gynecological surgery].
OBJECTIVE To assess the analgesic effect and side effects of PCA with lornoxicam compared with morphine and tramadol. METHODS 89 patients, scheduled for elective hysterectomy or hysteromyomectomy,Expand
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Thermal and photochemical epimerization/equilibration of carbohydrate cobaloximes.
Epimeric carbohydrate alkyl cobaloximes 4:5, 9:10, and 12:13 can be equilibrated thermally or photochemically. In each case, one isomer is strongly favored:Expand
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[Analysis of individualized primary prophylactic treatment of 19 cases of children with severe hemophilia A].
Objective: To study the current situation of primary prophylaxis in severe hemophilia A children and to explore rational regimen in order to provide evidence for the development of primaryExpand
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[An analysis of the evaluation results of symptom checklist 90 for female medical workers].
  • Z. Wang, Y. Ye, +6 authors L. Sun
  • Medicine
  • Zhonghua lao dong wei sheng zhi ye bing za zhi…
  • 20 October 2018
Objective: To evaluate the mental health of female doctors and nurses. Methods: Investigat the psychologic status of female doctors and nurses using symptom checklist 90. And statistical software wasExpand
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Field trials on mating disruption of Ostrinia furnacalis (Lep.: Pyralidae) with synthetic sex pheromones.
In the field trials conducted during 1984-85, 3 different doses of the sex pheromone of Asian corn borer, O. furnacalis, synthesized by the Jiangsu Institute of Pheromones, were used at 150,000 toExpand
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