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- Influence
Diagnosis of fibrosis and cirrhosis using liver stiffness measurement in nonalcoholic fatty liver disease
- V. Wong, J. Vergniol, +9 authors V. de Lédinghen
- Medicine
- Hepatology
- 1 February 2010
Nonalcoholic fatty liver disease (NAFLD) is one of the most common liver diseases in affluent countries. Accurate noninvasive tests for liver injury are urgently needed. The aim of this study was to… Expand
Disease progression of non-alcoholic fatty liver disease: a prospective study with paired liver biopsies at 3 years
Background Patients with non-alcoholic steatohepatitis (NASH) have increased mortality and liver-related complications. In contrast, simple steatosis is considered benign and non-progressive.… Expand
Quantitative elastography of liver fibrosis and spleen stiffness in chronic hepatitis B carriers: comparison of shear-wave elastography and transient elastography with liver biopsy correlation.
- Vivian Yee-fong Leung, J. Shen, +9 authors W. Chu
- Medicine
- Radiology
- 1 December 2013
PURPOSE
To document utility of shear-wave (SW) elastography for assessing liver fibrosis in chronic hepatitis B and to compare its performance with that of transient elastography.
MATERIALS AND… Expand
Molecular Characterization of the Fecal Microbiota in Patients with Nonalcoholic Steatohepatitis – A Longitudinal Study
Background The human gut microbiota has profound influence on host metabolism and immunity. This study characterized the fecal microbiota in patients with nonalcoholic steatohepatitis (NASH). The… Expand
Alanine aminotransferase‐based algorithms of liver stiffness measurement by transient elastography (Fibroscan) for liver fibrosis in chronic hepatitis B
Summary. The aim of this study is to know the liver stiffness measurement (LSM) cutoffs for different stages of liver fibrosis in chronic hepatitis B (CHB) and to investigate the effect of alanine… Expand
Histological severity and clinical outcomes of nonalcoholic fatty liver disease in nonobese patients
- J. C. Leung, Thomson Chi-Wang Loong, +7 authors V. Wong
- Medicine
- Hepatology
- 1 January 2017
Although nonalcoholic fatty liver disease (NAFLD) is closely linked to obesity, around 10%‐20% of nonobese Americans and Asians still develop NAFLD. Data on this special group are limited. We… Expand
Entecavir treatment reduces hepatic events and deaths in chronic hepatitis B patients With liver cirrhosis
- G. Wong, H. L. Chan, +9 authors V. Wong
- Medicine
- Hepatology
- 1 November 2013
Entecavir is a potent antiviral agent with high genetic barrier to resistance, hence it is currently recommended as first‐line antiviral therapy for chronic hepatitis B (CHB). The aim of this study… Expand
Bacterial Microbiota Profiling in Gastritis without Helicobacter pylori Infection or Non-Steroidal Anti-Inflammatory Drug Use
- Xiao-xing Li, G. Wong, +6 authors Chunming Ding
- Biology, Medicine
- PloS one
- 24 November 2009
Recent 16S ribosomal RNA gene (rRNA) molecular profiling of the stomach mucosa revealed a surprising complexity of microbiota. Helicobacter pylori infection and non-steroidal anti-inflammatory drug… Expand
Lengthening and shortening of plasma DNA in hepatocellular carcinoma patients
- P. Jiang, Carol W M Chan, +10 authors Y. Lo
- Biology, Medicine
- Proceedings of the National Academy of Sciences
- 2 February 2015
Significance We used massively parallel sequencing to study the size profiles of plasma DNA samples at single-base resolution and in a genome-wide manner. We used chromosome arm-level z-score… Expand
Prevalence of non-alcoholic fatty liver disease and advanced fibrosis in Hong Kong Chinese: a population study using proton-magnetic resonance spectroscopy and transient elastography
Objective Knowledge of the epidemiology of non-alcoholic fatty liver disease (NAFLD) is incomplete because liver biopsy cannot be performed on the general population to assess disease severity. New… Expand