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Definition, assessment and treatment of wheezing disorders in preschool children: an evidence-based approach
TLDR
Large well-designed randomised controlled trials with clear descriptions of patients are needed to improve the present recommendations on the treatment of these common syndromes.
International consensus on (ICON) pediatric asthma
TLDR
The purpose of this document is to highlight the key messages that are common to many of the existing guidelines, while critically reviewing and commenting on any differences, thus providing a concise reference.
West Sweden Asthma Study: Prevalence trends over the last 18 years argues no recent increase in asthma
TLDR
The data argues that the continued increase in asthma prevalence that has been observed over the last half century is over.
Combined effects of sleeping position and prenatal risk factors in sudden infant death syndrome: the Nordic Epidemiological SIDS Study.
TLDR
The risk of SIDS was increased further in low birth weight infants, preterm infants, and infants at the age of 13 to 24 weeks, suggesting that SIDS may be triggered by nonsupine sleeping in infants with prenatal risk factors during a vulnerable period of postnatal development.
Changes in the epidemiology of sudden infant death syndrome in Sweden 1973–1996
TLDR
In the data from the Medical Birth Registry of Sweden, there were significantly increased odds ratios after the risk reducing campaign of the risk factors smoking during early pregnancy and preterm birth, and odds ratios increased for smoking and prematurity.
Problematic severe asthma in children, not one problem but many: a GA2LEN initiative
TLDR
The term problematic severe asthma is used to describe children with any combination of chronic symptoms, acute severe exacerbations and persistent airflow limitation despite the prescription of multiple therapies.
Longitudinal follow‐up of growth in children born small for gestational age
TLDR
The prognosis for catch‐up growth for an SGA child, when children with well‐defined causes of growth disturbances are excluded, is very good and it is extremely rare for the child still to have a height below ‐2 SD by the age of 4 years.
Topical steroid treatment of allergic rhinitis decreases nasal fluid TH2 cytokines, eosinophils, eosinophil cationic protein, and IgE but has no significant effect on IFN-gamma, IL-1beta, TNF-alpha,
TLDR
The beneficial effects of topical treatment with GC in patients with allergic rhinitis could be attributed to downregulation of T(H)2 cytokines, with an ensuing decrease of eosinophils, ECP, and IgE.
Low levels of CC16 in nasal fluid of children with birch pollen‐induced rhinitis
TLDR
Cl Clara cell protein 16 (CC16; secretoglobin 1A1) is an anti‐inflammatory protein mainly expressed in the epithelial cells in the airways that is involved in inflammation and cell reprograming.
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