• Publications
  • Influence
NMRPipe: A multidimensional spectral processing system based on UNIX pipes
The NMRPipe system is a UNIX software environment of processing, graphics, and analysis tools designed to meet current routine and research-oriented multidimensional processing requirements and accommodate future demands and developments. Expand
  • 12,277
  • 482
  • PDF
Ca2+ regulation in the Na+/Ca2+ exchanger involves two markedly different Ca2+ sensors.
The plasma membrane Na+/Ca2+ exchanger (NCX) is almost certainly the major Ca2+ extrusion mechanism in cardiac myocytes. Binding of Na+ and Ca2+ ions to its large cytosolic loop regulates ionExpand
  • 159
  • 19
Ca2+ regulation in the Na+/Ca2+ exchanger features a dual electrostatic switch mechanism
Regulation of ion-transport in the Na+/Ca2+ exchanger (NCX) occurs via its cytoplasmic Ca2+-binding domains, CBD1 and CBD2. Here, we present a mechanism for NCX activation and inactivation based onExpand
  • 70
  • 17
The solution structure and DNA-binding properties of the cold-shock domain of the human Y-box protein YB-1.
The human Y-box protein 1 (YB-1) is a member of the Y-box protein family, a class of proteins involved in transcriptional and translational regulation of a wide range of genes. Here, we report theExpand
  • 115
  • 15
ATP-induced conformational changes of the nucleotide-binding domain of Na,K-ATPase
The Na,K-ATPase hydrolyzes ATP to drive the coupled extrusion and uptake of Na+ and K+ ions across the plasma membrane. Here, we report two high-resolution NMR structures of the 213-residueExpand
  • 95
  • 11
Solution structure and backbone dynamics of the photoactive yellow protein.
The solution structure of photoactive yellow protein (PYP), a photosensory protein from Ectothiorhodospira halophila, has been determined by multidimensional NMR spectroscopy. The structure consistsExpand
  • 116
  • 8
Solution structure of the DNA-binding domain of Drosophila heat shock transcription factor
The solution structure of the DNA-binding domain of the Drosophila heat shock transcription factor, as determined by multidimensional multinuclear NMR, resembles that of the helix-turn-helix class ofExpand
  • 64
  • 8
  • PDF
Structural diversity in twin-arginine signal peptide-binding proteins
The twin-arginine transport (Tat) system is dedicated to the translocation of folded proteins across the bacterial cytoplasmic membrane. Proteins are targeted to the Tat system by signal peptidesExpand
  • 74
  • 7
  • PDF
Measurement of homo- and heteronuclear J couplings from quantitative J correlation.
Publisher Summary This chapter discusses a third method, referred to as quantitative “ J correlation.” In this approach, the J coupling is obtained from the fraction of magnetization that isExpand
  • 352
  • 6
WeNMR: Structural Biology on the Grid
The WeNMR project is a European Union funded international effort to streamline and automate analysis of Nuclear Magnetic Resonance (NMR) and Small Angle X-Ray scattering (SAXS) imaging data for atomic and near-atomic resolution molecular structures. Expand
  • 159
  • 6
  • PDF