• Publications
  • Influence
An ethnobotanical survey of medicinal plants used in Loja and Zamora-Chinchipe, Ecuador.
TLDR
An ethnobotanical survey on the uses of medicinal plants by inhabitants of two southern Ecuadorian provinces, namely, Loja and Zamora-Chinchipe, reports a total of 275 plant species, having 68 different therapeutical uses. Expand
Electrophilic Cyclopentenone Neuroprostanes Are Anti-inflammatory Mediators Formed from the Peroxidation of the ω-3 Polyunsaturated Fatty Acid Docosahexaenoic Acid*
TLDR
It is demonstrated that A4/J4-NPs, formed via the oxidation of DHA, are potent inhibitors of NF-κB signaling and may contribute to the anti-inflammatory actions of D HA. Expand
Interaction of electrophilic lipid oxidation products with mitochondria in endothelial cells and formation of reactive oxygen species.
TLDR
It is proposed that ROS formation in endothelial cells is due to the direct interaction of these lipids with the organelle, an effect not observed by using a fluorescently labeled nonelectrophilic lipid. Expand
Neurotoxic lipid peroxidation species formed by ischemic stroke increase injury.
TLDR
This work demonstrates that 15-A(2t)-IsoP is abundantly produced in stroke-infarcted human cortical tissue and suggests that the addition of 15- a-2t- isoP to in vitro models of ischemia may help to more fully recapitulate stroke injury. Expand
Morphological and chemical studies on the pygidial defence glands of some Carabidae (Coleoptera)
Etude effectuee sur 4 especes Pterostichus externepunctatus roccai, Nebria psammodes, Chlaenius velutinus et Chlaenius vestitus
Chemical composition and antimicrobial activity of Myrcianthes fragrans essential oil, a natural aromatizer of the traditional Ecuadorian beverage colada morada.
TLDR
In vitro antimicrobial tests showed that the essential oils from M. fragrans exhibited good activity against the Gram-negative bacteria, K. pneumoniae, and against the yeasts, C. albicans and S. cerevisiae, suggesting a plausible scientific explanation for the traditional uses of the plant not only as a natural aromatizer of a traditional beverage but also as anatural anti-infective and anti-yeast agent. Expand
4-Alkyl- and 4-phenylcoumarins from Mesua ferrea as promising multidrug resistant antibacterials.
TLDR
Biological investigations towards the screening on a number of bacteria strains and Plasmodium falciparum, identified compounds 1-9 as weak antiprotozoal agents and potent antibacterials on resistant Gram-positive strains. Expand
Cyclopentenone Isoprostanes Inhibit the Inflammatory Response in Macrophages*
TLDR
It is suggested that cyclopentenone isoprostanes may serve as negative feedback regulators of inflammation and have important implications for defining the role of oxidative stress in the inflammatory response. Expand
Dialdehyde sesquiterpenes and other terpenoids as vanilloids.
TLDR
It is concluded that a range of sesquiterpene dialdehydes and related terpenoids, both pungent and non-pungent, may function as vanilloids. Expand
Anti-secretory, anti-inflammatory and anti-Helicobacter pylori activities of several fractions isolated from Piper carpunya Ruiz & Pav.
TLDR
It is suggested that the flavonoids isolated from F I and II contribute to the anti-MPO activity, as well as to their anti-Helicobacter pylori activity. Expand
...
1
2
3
4
5
...