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- Publications
- Influence
Oxidative stress in the hippocampus after pilocarpine‐induced status epilepticus in Wistar rats
- R. M. Freitas, S. Vasconcelos, F. Souza, G. Viana, M. Fonteles
- Chemistry, Medicine
- The FEBS journal
- 1 March 2005
The role of oxidative stress in pilocarpine‐induced status epilepticus was investigated by measuring lipid peroxidation level, nitrite content, GSH concentration, and superoxide dismutase and… Expand
Anticonvulsant activity of hydroalcoholic extracts from Erythrina velutina and Erythrina mulungu.
- S. Vasconcelos, N. M. Lima, +8 authors G. Viana
- Medicine
- Journal of ethnopharmacology
- 21 March 2007
The anticonvulsant effects of hydroalcoholic extracts (HAEs) from the stem bark of Erythrina velutina and Erythrina mulungu on pentylenetetrazole (PTZ) and strychnine-induced seizure tests and the… Expand
Effects of Levetiracetam in Lipid Peroxidation Level, Nitrite–Nitrate Formation and Antioxidant Enzymatic Activity in Mice Brain After Pilocarpine-Induced Seizures
- A. A. Oliveira, J. P. C. Almeida, +7 authors M. Fonteles
- Chemistry, Medicine
- Cellular and Molecular Neurobiology
- 5 January 2007
Oxidative stress has been implicated in a large number of human degenerative diseases, including epilepsy. Levetiracetam (LEV) is a new antiepileptic agent with broad-spectrum effects on seizures… Expand
Anti-inflammatory effects and possible mechanism of action of lupeol acetate isolated from Himatanthus drasticus (Mart.) Plumel
- D. L. Lucetti, Elaine CP Lucetti, +8 authors G. Viana
- Medicine
- Journal of Inflammation
- 17 December 2010
BackgroundThe species Himatanthus drasticus is popularly known in Northeast Brazil as "janaguba" and belongs to the family Apocynaceae. The latex collected from its stem bark is used for several… Expand
Pilocarpine-induced status epilepticus in rats: lipid peroxidation level, nitrite formation, GABAergic and glutamatergic receptor alterations in the hippocampus, striatum and frontal cortex
- R. M. Freitas, F. Sousa, S. Vasconcelos, G. Viana, M. Fonteles
- Chemistry, Medicine
- Pharmacology Biochemistry and Behavior
- 1 June 2004
The aim of the study was to investigate the lipid peroxidation levels, nitrite formation, GABAergic and glutamatergic receptor densities in the hippocampus, frontal cortex and striatum of Wistar rats… Expand
Behavioral and neurochemical effects on rat offspring after prenatal exposure to ethanol.
- L. M. Carneiro, J. Diógenes, +4 authors G. Viana
- Psychology, Medicine
- Neurotoxicology and teratology
- 1 July 2005
The work studied behavioral and neurochemical alterations in 21-day-old pups, from both sexes (26 g on average) born from female Wistar rats administered daily with ethanol (0.5 or 4.0 g/kg, p.o.),… Expand
Anxiolytic‐like effect of Carvacrol (5‐isopropyl‐2‐methylphenol) in mice: involvement with GABAergic transmission
- F. H. Melo, E. T. Venâncio, +4 authors F. D. de Sousa
- Chemistry, Medicine
- Fundamental & clinical pharmacology
- 10 November 2009
Carvacrol (5‐isopropyl‐2‐methylphenol) is a monoterpenic phenol present in the essencial oil of many plants. It is the major component of the essential oil fraction of oregano and thyme. This work… Expand
Attenuating effects of melatonin on pilocarpine-induced seizures in rats.
- L. Costa-Lotufo, M. Fonteles, +4 authors G. Viana
- Chemistry, Medicine
- Comparative biochemistry and physiology…
- 1 April 2002
Daily melatonin (10-50 mg/kg, i.p.) treatment at 08.30 h or 17.00 h for 1 week of female rats (2-months-old) increased the latency to the appearance of the first convulsion in the pilocarpine-induced… Expand
Piplartine, an amide alkaloid from Piper tuberculatum, presents anxiolytic and antidepressant effects in mice.
- F. Felipe, Jucélio Trajano Sousa Filho, +5 authors G. Viana
- Chemistry
- 3 September 2007
In the present work, we studied the effects of piplartine (PIP), an amide alkaloid isolated from the roots of Piper tuberculatum (Piperaceae), in the elevated plus maze, open field, rota rod,… Expand
A possible mechanism for anxiolytic and antidepressant effects of alpha- and beta-amyrin from Protium heptaphyllum (Aubl.) March
- G. F. Aragão, L. M. Carneiro, A. P. F. Junior, L. Vieira, G. Viana
- Chemistry, Medicine
- Pharmacology Biochemistry and Behavior
- 1 December 2006
In the present study, we examined the anxiolytic and antidepressant effects of the mixture of alpha- and beta-amyrin (AMY), pentacyclic triterpenes isolated from the stem bark resin of Protium… Expand