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Towards More Realistic In Vitro Release Measurement Techniques for Biodegradable Microparticles
TLDR
Great care must be taken when defining the in vitro conditions for drug release measurements from biodegradable microparticles, due to the small size of the drug molecules/ions with respect to the hydrogel mesh size. Expand
Determination of glyphosate in biological fluids by 1H and 31P NMR spectroscopy.
TLDR
Characterization of the N-(phosphonomethyl) glycine herbicide was achieved by chemical shift considerations and coupling constant patterns, confirming the ingestion of the considered trade formulation. Expand
Use of 15N reverse gradient two-dimensional nuclear magnetic resonance spectroscopy to follow metabolic activity in Nicotiana plumbaginifolia cell-suspension cultures
TLDR
The occurrence of 15N-label in agmatine and the low detection of labelled putrescine indicate that crucial intermediates of the pathway from glutamate to polyamines and/or the tobacco alkaloids could be monitored. Expand
1H-NMR analysis of trimethylamine in urine for the diagnosis of fish-odour syndrome.
TLDR
The use of proton NMR spectroscopy for the analysis of trimmedethylamine in the urine of a patient with trimethylaminuria and analysis was also performed for other members of his family. Expand
Kinetic and structural studies of the photochromic process of 3H-naphthopyrans by UV and NMR spectroscopy
The photomerocyanines resulting from the UV irradiation of closed colourless 3,3-diphenyl-3H-naphtho[2,1-b]pyran and its 3,3-bis(4-fluorophenyl) derivative have been studied by UV–VIS and NMRExpand
Identification and quantitation of xenobiotics by 1H NMR spectroscopy in poisoning cases.
TLDR
NMR investigations were applied to acute poisoning cases, involving drugs such as salicylates and valproic acid, and an intentional poisoning case with tetrahydrofuran, which allowed the determination of many exogenous and endogenous compounds, without any pre-selection of the analytes. Expand
TYPE I and TYPE II PHOTOSENSITIZATION BY THE ANTIBACTERIAL DRUG NALIDIXIC ACID. A LASER FLASH PHOTOLYSIS STUDY *
TLDR
The physiological form of nalidixic acid is a good Type I and Type II photosensitizer and is characterized by its reactions with ferricytochrome c and superoxide dismutase. Expand
Configurational stability of 9-hydroxyrisperidone. Kinetics and mechanism of racemization
Abstract The configurational stability of 9-hydroxyrisperidone, an atypical antipsychotic, was studied under acidic, basic and physiological conditions. The analysis of 9-hydroxyrisperidone wasExpand
Photochromism of 8-thienyl-naphthopyrans investigated by NMR spectroscopy
The photochromism of four 8-thienyl-naphthopyrans substituted either directly or via an acetylenic bridge to one or two thienyl groups, has been investigated by NMR spectroscopy. The two expectedExpand
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