Intensive insulin therapy in the medical ICU.
- G. Van den Berghe, A. Wilmer, R. Bouillon
- MedicineNew England Journal of Medicine
- 11 May 2006
Intensive insulin therapy significantly reduced morbidity but not mortality among all patients in the medical ICU, and the risk of subsequent death and disease was reduced in patients treated for three or more days.
Intensive insulin therapy in critically ill patients.
- G. Van den Berghe, P. Wouters, R. Bouillon
- MedicineNew England Journal of Medicine
- 1 October 2001
Intensive insulin therapy to maintain blood glucose at or below 110 mg per deciliter reduces morbidity and mortality among critically ill patients in the surgical intensive care unit.
Guidelines on diabetes, pre-diabetes, and cardiovascular diseases: executive summary. The Task Force on Diabetes and Cardiovascular Diseases of the European Society of Cardiology (ESC) and of the…
Guidelines and Expert Consensus documents aim to present management and recommendations based on all of the relevant evidence on a particular subject in order to help physicians to select the best…
ESPEN Guidelines on Enteral Nutrition: Intensive care.
- K. G. Kreymann, M. Berger, C. Spies
- MedicineClinical Nutrition
- 2006
Management of hyperglycemia in hospitalized patients in non-critical care setting: an endocrine society clinical practice guideline.
- G. Umpierrez, Richard Hellman, G. Van den Berghe
- MedicineJournal of Clinical Endocrinology and Metabolism
- 2012
This evidence-based guideline provides recommendations for practical, achievable, and safe glycemic targets and describes protocols, procedures, and system improvements required to facilitate the achievement of glycemic goals in patients with hyperglycemia and diabetes admitted in non-critical care settings.
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
- D. Klionsky, K. Abdelmohsen, S. Zughaier
- BiologyAutophagy
- 18 April 2012
There continues to be confusion regarding acceptable methods to measure autophagy, especially in multicellular eukaryotes, so it is important to update guidelines for monitoring autophagic activity in different organisms.
Early versus late parenteral nutrition in critically ill adults.
- M. Casaer, D. Mesotten, G. Van den Berghe
- MedicineNew England Journal of Medicine
- 10 August 2011
Late initiation of parenteral nutrition was associated with faster recovery and fewer complications, as compared with early initiation.
Insulin therapy protects the central and peripheral nervous system of intensive care patients
- G. Van den Berghe, K. Schoonheydt, P. Becx, F. Bruyninckx, P. Wouters
- MedicineNeurology
- 26 April 2005
Preventing even moderate hyperglycemia with insulin during intensive care protected the central and peripheral nervous systems, with clinical consequences such as shortening of intensive care dependency and possibly better long-term rehabilitation.
Clinical review: intensive care unit acquired weakness
- G. Hermans, G. Van den Berghe
- MedicineCritical Care
- 5 August 2015
Prognosis appears compromised when the cause of ICUAW involves critical illness polyneuropathy, whereas isolated critical illness myopathy may have a better prognosis.
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