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Spatial and temporal activation of spinal glial cells: Role of gliopathy in central neuropathic pain following spinal cord injury in rats
In the spinal cord, neuron and glial cells actively interact and contribute to neurofunction. Surprisingly, both cell types have similar receptors, transporters and ion channels and also produce… Expand
Acute and chronic changes in aquaporin 4 expression after spinal cord injury
The effect of spinal cord injury (SCI) on the expression levels and distribution of water channel aquaporin 4 (AQP4) has not been studied. We have found AQP4 in gray and white matter astrocytes in… Expand
Aquaporin 1 – a novel player in spinal cord injury
The role of water channel aquaporin 1 (AQP‐1) in uninjured or injured spinal cords is unknown. AQP‐1 is weakly expressed in neurons and gray matter astrocytes, and more so in white matter astrocytes… Expand
Transcriptional profiling of spinal cord injury‐induced central neuropathic pain
Central neuropathic pain (CNP) is an important problem following spinal cord injury (SCI), because it severely affects the quality of life of SCI patients. As in the patient population, the majority… Expand
Propentofylline attenuates allodynia, glial activation and modulates GABAergic tone after spinal cord injury in the rat
&NA; In this study, we evaluated whether propentofylline, a methylxanthine derivative, modulates spinal glial activation and GABAergic inhibitory tone by modulation of glutamic acid decarboxylase… Expand
Nuclear factor‐κB decoy amelioration of spinal cord injury‐induced inflammation and behavior outcomes
- D. S. Rafati, K. Geissler, +4 authors J. Perez-polo
- Chemistry, Medicine
- Journal of neuroscience research
- 15 February 2008
Spinal cord injury (SCI) results in a pathophysiology characterized by multiple locomotor and sensory deficits, resulting in altered nociception and hyperalgesia. SCI triggers an early and prolonged… Expand
Application of the avidin-biotin-peroxidase complex (ABC) method to the light microscopic localization of pituitary hormones.
The avidin-biotin-peroxidase complex (ABC) method was applied to semithin (0.5-1 micron) plastic-embedded sections of intact male rat pituitaries with the use of techniques previously developed for… Expand
Cytological factors that support nonparallel secretion of luteinizing hormone and follicle-stimulating hormone during the estrous cycle.
Gonadotropes from cycling female rats were studied to investigate possible mechanisms for the nonparallel release of LH and FSH. The percentages of total gonadotropes increased from 14% during estrus… Expand
Differential expression of growth hormone messenger ribonucleic acid by somatotropes and gonadotropes in male and cycling female rats.
Past studies have reported the appearance of cells sharing phenotypic characteristics of gonadotropes and GH cells. During diestrus and early proestrus, a subset of somatotropes (40-60%) expressed… Expand
Inflammatory consequences in a rodent model of mild traumatic brain injury.
Mild traumatic brain injury (mTBI), particularly mild "blast type" injuries resulting from improvised exploding devices and many sport-caused injuries to the brain, result in long-term impairment of… Expand