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Trace Element Levels in Hashimoto Thyroiditis Patients with Subclinical Hypothyroidism
TLDR
None of these biochemical risk factors and trace elements have changed after euthyroidism in patients with SH when compared to pretreatment levels. Expand
Is leptin associated with diabetic retinopathy?
TLDR
Leptin-induced promotion of angiogenesis and neovascularization lends support to the possibility that leptin may play a role in the progression of human diabetic retinopathy to a proliferative phase, even after adjusting the leptin levels for BMI. Expand
HDR syndrome (hypoparathyroidism, sensorineural deafness and renal disease) accompanied by renal tubular acidosis and endocrine abnormalities.
TLDR
A 19-year-old man is described with HDR syndrome accompanied by renal tubular acidosis and endocrinopathic changes, defined by the triad hypoparathyroidism, renal dysplasia and hearing loss. Expand
Adipose tissue 11-beta-Hydroxysteroid Dehydrogenase Type 1 and Hexose-6-Phosphate Dehydrogenase gene expressions are increased in patients with type 2 diabetes mellitus.
TLDR
Failure to down-regulate HSD11B1 activity in patients with type 2 diabetes may contribute to the pathogenesis of T2DM. Expand
Plasma leptin levels strongly correlate with plasma renin activity in patients with essential hypertension.
TLDR
The results showed that elevated plasma leptin and PRA are associated with hypertension in both lean and overweight/obese hypertensives, and suggest that adipose mass is an important determinant of blood pressure, although the mechanism is not clear. Expand
Dynamic changes in {beta}-cell mass and pancreatic insulin during the evolution of nutrition-dependent diabetes in psammomys obesus: impact of glycemic control.
TLDR
It is concluded that reduced insulin reserve is the main cause of diabetes progression, whereas irreversible beta-cell mass reduction is a late event in P. obesus, a model for nutrition-dependent type 2 diabetes. Expand
Plasma Apelin and ADMA Levels in Patients with Essential Hypertension
TLDR
A group of newly diagnosed and untreated 30 young hypertensive men and 30 healthy controls investigated the role of ADMA and apelin in the pathogenesis of essential hypertension, finding the levels were significantly lower and the ADMA levels higher in the patients. Expand
Defective antioxidant defense system in patients with a human leptin gene mutation.
TLDR
The results demonstrate that the activity of antioxidant enzymes and plasma levels of Se, Zn and Mn levels were decreased in both homozygous and heterozygous subjects with leptin gene mutation, and suggest that both leptin and trace elements might be involved in the modulation of antioxidant defense system. Expand
High plasma level of long Pentraxin 3 is associated with insulin resistance in women with polycystic ovary syndrome
Objectives: Polycystic ovary syndrome (PCOS) is characterized by insulin resistance. Chronic low-grade inflammation has been anticipated to play role in the pathogenesis of both insulin resistanceExpand
The relationship of epicardial adipose tissue thickness to clinical and biochemical features in women with polycystic ovary syndrome.
TLDR
Thickness of the EAT is increased in patients with PCOS in conjunction with hyperandrogenity, and Prospective studies are required to identify the relation of EAT and cardiovascular risk in patientswith PCOS. Expand
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