G. Tytgat

Publications826
h-index103
Citations43,112
Highly Influential Citations937
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Functional gastroduodenal disorders.
While widely used in research, the 1991 Rome criteria for the gastroduodenal disorders, especially symptom subgroups in dyspepsia, remain contentious. After a comprehensive literature search, a… Expand
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The genetic basis of the reduced expression of bilirubin UDP-glucuronosyltransferase 1 in Gilbert's syndrome.
BACKGROUND People with Gilbert's syndrome have mild, chronic unconjugated hyperbilirubinemia in the absence of liver disease or overt hemolysis. Hepatic glucuronidating activity, essential for… Expand
  • 1,323
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Endoscopic assessment of oesophagitis: clinical and functional correlates and further validation of the Los Angeles classification
BACKGROUND Endoscopic oesophageal changes are diagnostically helpful and identify patients exposed to the risk of disease chronicity. However, there is a serious lack of agreement about how to… Expand
  • 1,722
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The endoscopic assessment of esophagitis: a progress report on observer agreement.
BACKGROUND & AIMS The study and management of reflux esophagitis require an endoscopic classification system founded on esophageal lesions that can be reproducibly identified. The aim of this study… Expand
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Barrett's esophagus: development of dysplasia and adenocarcinoma.
Barrett's esophagus is considered to be a premalignant condition, and long-term surveillance seems mandatory with a careful search for dysplasia and carcinoma by means of multiple and repeated sets… Expand
  • 863
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Randomised trial of self-expanding metal stents versus polyethylene stents for distal malignant biliary obstruction
Self-expanding metal stents are claimed to prolong biliary-stent patency, although no formal comparative trial between plastic and expandable stents has been done. In a prospective randomised trial,… Expand
  • 877
  • 18
The efficacy of endoscopic treatment of pancreatic pseudocysts.
BACKGROUND Endoscopic drainage of pancreatic pseudocysts is a new nonsurgical treatment modality. We retrospectively studied the efficacy of endoscopic drainage of pseudocysts in 37 patients with… Expand
  • 226
  • 16
Mucosal tumor necrosis factor-alpha, interleukin-1 beta, and interleukin-8 production in patients with Helicobacter pylori infection.
We investigated whether tumor necrosis factor-alpha (TNF-alpha), interleukin-1 beta (IL-1 beta), and interleukin-8 (IL-8) are involved in the inflammatory reaction of Helicobacter pylori infection.… Expand
  • 529
  • 14
Natural history of primary sclerosing cholangitis and prognostic value of cholangiography in a Dutch population
Background: Median survival of patients with primary sclerosing cholangitis (PSC) has been estimated to be 12 years. Cholangiography is the gold standard for diagnosis but is rarely used in… Expand
  • 210
  • 14
  • PDF
Intragastric balloon for treatment-resistant obesity: safety, tolerance, and efficacy of 1-year balloon treatment followed by a 1-year balloon-free follow-up.
BACKGROUND Prior efforts to treat obesity with intragastric balloons were thwarted by high complication rates. Therefore, fundamental requirements for optimal balloon designs were defined. The aim of… Expand
  • 206
  • 13