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Current concepts in the management of Helicobacter pylori infection—The Maastricht 2‐2000 Consensus Report
TLDR
The European Helicobacter Pylori Study Group organized a meeting of specialists and experts from around the world, representatives from National Gastroenterology Societies and general practitioners from Europe to establish updated guidelines on the current management of Helicobacteria pylori infection.
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Barrett's esophagus: development of dysplasia and adenocarcinoma.
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A mutation in the human canalicular multispecific organic anion transporter gene causes the Dubin‐Johnson syndrome
TLDR
The human homologue of rat cmoat, human cMOAT, is isolated and analyzed the corresponding cDNA from fibroblasts of a DJS patient for mutations, showing that a mutation in this gene is the cause of DJS.
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The Sydney System: Endoscopic division. Endoscopic appearances in gastritis/duodenitis
  • G. Tytgat
  • Medicine
    Journal of gastroenterology and hepatology
  • 1 June 1991
TLDR
The role of endoscopy should be discussed and whether it is appropriate that the endoscopist uses the terms ‘gastritis’ and ‘duodenitis’ to indicate macroscopic changes of the mucosal lining, or whether the terms should be reserved only for histologically demonstrable inflanunatory changes.
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Mucosal tumor necrosis factor-alpha, interleukin-1 beta, and interleukin-8 production in patients with Helicobacter pylori infection.
TLDR
A strong correlation was found between the production of IL-1 beta and IL-8 and the biologic effects of these cytokines may explain the conspicuous recruitment, influx, and activation of neutrophils in the gastric mucosa during H. pylori infection.
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Sonic hedgehog regulates gastric gland morphogenesis in man and mouse.
TLDR
Shh controls the expression of at least 3 factors important for epithelial differentiation and is a negative regulator of gastric gland cell proliferation, which makes it a candidate polarizing signal in the maintenance of Gastric pit-gland asymmetry.
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Natural history of primary sclerosing cholangitis and prognostic value of cholangiography in a Dutch population
TLDR
The observed survival in Dutch PSC patients with established PSC was considerably better than reported in earlier series from Sweden, the UK, and the USA.
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Randomised trial of endoscopic balloon dilation versus endoscopic sphincterotomy for removal of bileduct stones
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Inhibition of stress-activated MAP kinases induces clinical improvement in moderate to severe Crohn's disease.
TLDR
Inflammatory MAPKs are critically involved in the pathogenesis of Crohn's disease and their inhibition provides a novel therapeutic strategy, and treatment resulted in diminished JNK phosphorylation and tumor necrosis factor production as well as significant clinical benefit and rapid endoscopic ulcer healing.
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HLA-DR and -DQ phenotypes in inflammatory bowel disease: a meta-analysis
TLDR
Both ulcerative colitis and Crohn’s disease are associated with specific HLA class II phenotypes, and further analysis of these phenotypes and subgroup analysis may elucidate how these alleles contribute to susceptibility to IBD.
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