• Publications
  • Influence
Animal models of atherosclerosis
Different species of atherosclerosis models are outlined, with discussions on the practicality of their use for experimentation, and their advantages and disadvantages. Expand
The significance of the Wnt pathway in the pathology of human cancers.
There are several regulatory mechanisms for the down-regulation of the Wnt/beta-catenin signal, perhaps reflecting the pivotal nature of the pathway and the detrimental consequences of inappropriate activation. Expand
Estrogen and Its Receptors in Cancer
Estrogen and its receptors in cancer
The role and function of estrogens and its receptors in cancers of three categories are discussed: (1) Breast cancer and gynecologic cancers, (2) Cancers of endocrine organs, (3) Lung cancer and cancers of digestive system. Expand
Association Between Bacteremia From Specific Microbes and Subsequent Diagnosis of Colorectal Cancer.
A retrospective analysis of patients hospitalized for bacteremia associated later diagnosis of CRC with B fragilis and S gallolyticus and other intestinal microbes support a model in which specific members of the intestinal microbiota promote colorectal carcinogenesis. Expand
Empagliflozin, a sodium glucose co-transporter-2 inhibitor, alleviates atrial remodeling and improves mitochondrial function in high-fat diet/streptozotocin-induced diabetic rats
Empagliflozin can ameliorate atrial structural and electrical remodeling as well as improve mitochondrial function and mitochondrial biogenesis in T2DM, hence may be potentially used in the prevention of T2 DM-related atrial fibrillation. Expand
Meta-analysis of Fragmented QRS as an Electrocardiographic Predictor for Arrhythmic Events in Patients with Brugada Syndrome
It was showed that BrS patients with fQRS are at high risk for future arrhythmic events, and the presence of f QRS warrants prospective evaluation as valid arrhythmogenic risk marker in BrS. Expand
Mouse models of atherosclerosis: a historical perspective and recent advances
The different mouse models for the study and elucidation of the pathophysiological mechanisms underlying atherosclerosis are examined and recent advances in the field, such as the role of oxidative stress in promoting endoplasmic reticulum stress, mitochondrial dysfunction and mitochondrial DNA damage, are reviewed. Expand
Mechanisms of cardiac arrhythmias
  • G. Tse
  • Medicine
  • Journal of arrhythmia
  • 17 December 2015
A brief outline of the different classification systems for arrhythmogenesis is provided, followed by a detailed discussion for each mechanism in turn, highlighting recent advances in this area. Expand
Induction of colitis and rapid development of colorectal tumors in mice deficient in the neuropeptide PACAP
A new mouse model which rapidly develops inflammation‐associated colorectal cancer in the absence of a carcinogen is demonstrated, demonstrating the role of the endogenous peptide in regulating immune function is unknown. Expand