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Comprehensive Molecular Portraits of Invasive Lobular Breast Cancer
Invasive lobular carcinoma (ILC) is the second most prevalent histologic subtype of invasive breast cancer. Here, we comprehensively profiled 817 breast tumors, including 127 ILC, 490 ductal (IDC),… Expand
Breast cancer prognostic classification in the molecular era: the role of histological grade
Breast cancer is a heterogeneous disease with varied morphological appearances, molecular features, behavior, and response to therapy. Current routine clinical management of breast cancer relies on… Expand
Animal models of atherosclerosis
Atherosclerosis is a significant cause of morbidity and mortality globally. Many animal models have been developed to study atherosclerosis, and permit experimental conditions, diet and environmental… Expand
Phyllodes tumor of the breast: an update
Phyllodes tumor is an uncommon biphasic breast tumor, with the ability to recur and metastasize, and it behaves biologically like a stromal neoplasm. Traditionally, phyllodes tumors are graded by the… Expand
The significance of the Wnt pathway in the pathology of human cancers.
The wingless-type (Wnt) signalling transduction pathway is essentially a network of a number of separate but interacting pathways. Specific Wnt ligands bind to their target 'frizzled' membrane… Expand
Hamartoma of the breast: a clinicopathological review
Aims: To review 25 cases of breast hamartoma and discuss the pathological criteria, and the usefulness of imaging modalities, fine needle aspiration cytology (FNAC), and needle core biopsy in the… Expand
Hormone receptor and c-ERBB2 status in distant metastatic and locally recurrent breast cancer. Pathologic correlations and clinical significance.
- Pushpalatha K A Idirisinghe, A. A. Thike, +5 authors P. Tan
- American journal of clinical pathology
- 1 March 2010
Estrogen receptor (ER), progesterone receptor (PR), and c-ERBB2 (HER2/neu) are therapeutically and prognostically important markers in the management of breast carcinoma. They are not always analyzed… Expand
Granulomatous mastitis: a clinicopathological review of 26 cases
Aims: Twenty‐six cases of granulomatous mastitis were examined to determine the common histological and clinical features and the possible association with micro‐organisms. Methods: A retrospective… Expand
Loss of androgen receptor expression predicts early recurrence in triple-negative and basal-like breast cancer
Treatment of triple-negative invasive breast cancers, defined by the absence of estrogen and progesterone receptors and c-erbB2 expression, remains challenging. Androgen receptor, a member of the… Expand