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Circulating Vδ1 + T cells are activated and accumulate in the skin of systemic sclerosis patients
OBJECTIVE: An increased percentage of Vdelta1+/gamma/delta T cells has been detected both in the peripheral blood and bronchoalveolar lavage fluid of patients with systemic sclerosis (SSc). ThisExpand
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Circulating levels of soluble CD30 are increased in patients with systemic sclerosis (SSc) and correlate with serological and clinical features of the disease
Activated Th2 lymphocytes express the surface molecule CD30 and release a soluble form of the same molecule which can be detected both in vivo and in vitro. In the present study, high levels ofExpand
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Peripheral blood mononuclear cells of patients with systemic sclerosis produce increased amounts of interleukin 6, but not transforming growth factor beta 1.
OBJECTIVE To assess the ability of peripheral blood mononuclear cells (PBMC) of patients with systemic sclerosis (SSc) to produce interleukin 6 (IL-6), transforming growth factor beta 1 (TGF-beta 1),Expand
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Circulating Vdelta1+ T cells are activated and accumulate in the skin of systemic sclerosis patients.
OBJECTIVE An increased percentage of Vdelta1+/gamma/delta T cells has been detected both in the peripheral blood and bronchoalveolar lavage fluid of patients with systemic sclerosis (SSc). This studyExpand
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Increase of circulating gamma/delta T lymphocytes in the peripheral blood of patients affected by active inflammatory bowel disease.
In order to study the role of gamma/delta T cells in the pathogenesis of inflammatory bowel disease (IBD) in humans, we measured the percentage of these cells in the peripheral blood, assessed theExpand
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Circulating gamma/delta T lymphocytes from systemic sclerosis (SSc) patients display a T helper (Th) 1 polarization.
Systemic sclerosis (SSc) is a connective tissue disease in which immune system activation is evidenced by high levels of different cytokines in the sera and/or in the supernatants of culturedExpand
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Natural killer activity and antibody‐dependent cellular cytotoxicity in progressive systemic sclerosis
Enhanced natural killer (NK) activity and normal lymphocyte antibody‐dependent cellular cytotoxicity (ADCC) were observed in 16 patients with a diagnosis of progressive systemic sclerosis (PSS).Expand
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Pathogenesis of immune complex glomerulonephritis of New Zealand mice.
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Immune complex disease associated with spontaneous murine leukemia: Incidence and pathogenesis of glomerulonephritis☆
Glomerulonephritis accompanies a large proportion of murine leukemia viral infections. AKR mice, which spontaneously developed leukemia after natural infection by Gross murine leukemia virus showedExpand
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HNK-1 monoclonal antibody (Leu-7) in the identification of abnormal expansions of large granular lymphocytes.
Among 12 cases of chronic T lymphoproliferative disorders we observed, six patients showed an expansion of mononuclear cells with azurophilic granules usually referred to as large granularExpand
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