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Coagulation factor XIII polymorphisms and the risk of myocardial infarction and ischaemic stroke in young women
Summary. The inconsistent findings among association studies that have examined the relationship between factor XIIIA Val34Leu and thrombosis may be owing to (1) population differences in theExpand
Analysis of platelet glycoprotein Ia (alpha2 integrin) allele frequencies in three North American populations reveals genetic association between nucleotide 807C/T and amino acid 505 Glu/Lys (HPA-5)
Glycoprotein Ia (alpha2 integrin) is a subunit of the heterodimeric membrane complex (GPIa/IIa) that mediates platelet adhesion to collagen. Several nucleotide sequence variations of GPIa have beenExpand
Red blood cell antigen genotype analysis for 9087 Asian, Asian American, and Native American blood donors
There has yet to be a comprehensive analysis of blood group antigen prevalence in Asian Americans and Native Americans. There may be ethnic differences in blood group frequencies that would result inExpand
Polymorphisms of Coagulation Factor XIII Subunit A and Risk of Nonfatal Hemorrhagic Stroke in Young White Women
Background and Purpose— Although family studies have suggested a genetic influence on hemorrhagic stroke, the underlying genetic risk factors remain poorly defined. Coagulation factor XIII, which isExpand
Bone marrow changes mimicking myelodysplasia in patients with hemophagocytic lymphohistiocytosis.
In hemophagocytic lymphohistiocytosis (HLH), cytokine-induced pancytopenia is a common finding and is associated with hypoplastic and hypocellular bone marrow and abundant hemophagocytosis. To date,Expand
Molecular blood typing augments serologic testing and allows for enhanced matching of red blood cells for transfusion in patients with sickle cell disease
BACKGROUND: Sickle cell disease (SCD) patients have dissimilar red blood cell (RBC) phenotypes compared to the primarily Caucasian blood donor base due, in part, to underlying complex Rh and silencedExpand
Complex Changes in von Willebrand Factor-Associated Parameters Are Acquired during Uncomplicated Pregnancy
Background The coagulation protein von Willebrand Factor (VWF) is known to be elevated in pregnancy. However, the timing and nature of changes in VWF and associated parameters throughout pregnancyExpand
Safety evaluation of a lyophilized platelet‐derived hemostatic product
Hemorrhage causes significant morbidity and mortality in people aged <65 years. A lyophilized platelet‐derived hemostatic agent (Thrombosomes) demonstrated hemostatic efficacy in animal models. WeExpand
Report on the Sixth International Society of Blood Transfusion Platelet Serology Workshop
Background: The Sixth International Society of Blood Transfusion Platelet Serology Workshop continued studies to identify methods to detect platelet‐specific antigens and antibodies.
Genomic characterization of the RH locus detects complex and novel structural variation in multi-ethnic cohorts
PurposeRh antigens can provoke severe alloimmune reactions, particularly in high-risk transfusion contexts, such as sickle cell disease. Rh antigens are encoded by the paralogs, RHD and RHCE, locatedExpand