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Inherited deficiency of the fourth component of human complement.
The highly polymorphic fourth component of human complement (C4) is usually encoded by two genes, C4A and C4B, adjacent to the 21-hydroxylase (21-OH) genes, and is also remarkable by the highExpand
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Carcinoembryonic antigen (CEA) in gastrointestinal and extragastrointestinal tumors and its relationship to tumor‐cell differentiation
Carcinomas of gastrointestinal (colon, stomach, pancreas, liver) and of extragastrointestinal (bronchus, breast, tonsil, anus, ovary) origin and normal large‐bowel mucosa were studied by indirectExpand
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Cardiovascular autonomic function, autoantibodies, and esophageal motor activity in patients with systemic sclerosis and mixed connective tissue disease.
OBJECTIVE To study cardiovascular autonomic nerve function and presence of autoantibodies in relation to esophageal motor activity in patients with systemic sclerosis (SSc) and mixed connectiveExpand
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Carcinoembryonic antigen and blood group substances in carcinomas of the stomach and colon.
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Blood group substances (BG) as carcinofetal antigens in carcinomas of the distal colon.
Abstract Colonic adenocarcinomas were studied for the presence of blood group substances (BG) using the mixed cell agglutination reaction (MCAR). Forty five to 68% of colonic carcinomas containedExpand
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The immunopathology of herpes gestationis. Immunofluorescence studies and characterization of "HG factor".
Nine skin biopsies from seven herpes gestationis patients were studied by immunofluorescence (IF) techniques. Basement membrane zone (BMZ) deposition of C3 and properdin was present in all nine skinExpand
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  • Open Access
Systemic lupus erythematosus in hereditary deficiency of the fourth component of complement.
Three patients from two families with complete hereditary deficiency of the fourth component of complement (C4) and systemic lupus erythematosus are described. The syndrome presented by theseExpand
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Assessment of pain in herpes zoster: lessons learned from antiviral trials.
Pain typically accompanies acute herpes zoster and, in a proportion of patients, it persists well beyond rash healing. Pain must therefore be analyzed in trials of antiviral agents in herpes zoster,Expand
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  • Open Access
Detection of disease-specific restriction fragment length polymorphisms in pemphigus vulgaris linked to the DQw1 and DQw3 alleles of the HLA-D region.
Pemphigus vulgaris in Israeli Ashkenazi and non-Ashkenazi Jews and in Austrian non-Jewish patients is strongly associated with the DR4 and DRw6 alleles of the HLA-D region class II genes. RestrictionExpand
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Genetic deficiency of C4, C2 or C1q and lupus syndromes. Association with anti-Ro (SS-A) antibodies.
Sera from 15 patients with genetically determined complement component deficiencies were studied for the presence of antibodies to various nuclear antigens. One of three patients with C2 deficiencyExpand
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