G. Tamiya

Publications159
h-index35
Citations5,103
Highly Influential Citations166
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Tumour necrosis factor α signalling through activation of Kupffer cells plays an essential role in liver fibrosis of non-alcoholic steatohepatitis in mice
Background: While tumour necrosis factor α (TNF-α) appears to be associated with the development of non-alcoholic steatohepatitis (NASH), its precise role in the pathogenesis of NASH is not well… Expand
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Reduced neuron-specific expression of the TAF1 gene is associated with X-linked dystonia-parkinsonism.
X-linked dystonia-parkinsonism (XDP) is a movement disorder endemic to the Philippines. The disease locus, DYT3, has been mapped to Xq13.1. In a search for the causative gene, we performed genomic… Expand
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Functional anatomy of the basal ganglia in X‐linked recessive dystonia‐parkinsonism
Dystonia is a neurological syndrome characterized by sustained muscle contractions that produce repetitive twisting movements or abnormal postures. X‐linked recessive dystonia parkinsonism (XDP;… Expand
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Natural selection and population history in the human angiotensinogen gene (AGT): 736 complete AGT sequences in chromosomes from around the world.
Several lines of evidence suggest that patterns of genetic variability in the human angiotensinogen gene (AGT) contribute to phenotypic variability in human hypertension. The A(-6) promoter variant… Expand
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A mutation of COX6A1 causes a recessive axonal or mixed form of Charcot-Marie-Tooth disease.
Charcot-Marie-Tooth disease (CMT) is the most common inherited neuropathy characterized by clinical and genetic heterogeneity. Although more than 30 loci harboring CMT-causing mutations have been… Expand
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Gene expression profiling of Japanese psoriatic skin reveals an increased activity in molecular stress and immune response signals
Gene expression profiling was performed on biopsies of affected and unaffected psoriatic skin and normal skin from seven Japanese patients to obtain insights into the pathways that control this… Expand
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Integrative Annotation of 21,037 Human Genes Validated by Full-Length cDNA Clones
The human genome sequence defines our inherent biological potential; the realization of the biology encoded therein requires knowledge of the function of each gene. Currently, our knowledge in this… Expand
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Hepatic AdipoR2 signaling plays a protective role against progression of nonalcoholic steatohepatitis in mice
It is unclear how hepatic adiponectin resistance and sensitivity mediated by the adiponectin receptor, AdipoR2, contributes to the progression of nonalcoholic steatohepatitis (NASH). The aim of this… Expand
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Nucleotide sequencing analysis of the 146-kilobase segment around the IkBL and MICA genes at the centromeric end of the HLA class I region.
To elucidate the complete gene structure and to identify new genes involved in the development of HLA class I antigen-associated diseases in the class I region of the human major histocompatibility… Expand
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Genome sequencing analysis of the 1.8 Mb entire human MHC class I region
Summary: The human MHC class I region spans 1.8 Mb from the MICB gene to the HLA‐F gene at the telomeric end of the HLA region. There are fewer genes recognized in this region than in the class II or… Expand
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