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Survival and causes of death in 366 Hungarian patients with systemic sclerosis
Objective: Survival analysis of a series of 366 consecutive patients with systemic sclerosis (SSc). Methods: Clinical and laboratory data were evaluated from 1983 until 2005 using a standardExpand
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Novel Biomarkers in Autoimmune Diseases
Abstract:  The development of autoimmune diseases may be influenced by hormonal, immunomodulatory, and metabolic pathways. Prolactin (PRL), ferritin, vitamin D, and the tumor marker tissueExpand
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Association of systemic and thyroid autoimmune diseases
Objective: There are few large cohort studies available on the association of systemic and thyroid autoimmune diseases. In this study, we wished to determine the association of Hashimoto’sExpand
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Endothelial dysfunction precedes atherosclerosis in systemic sclerosis--relevance for prevention of vascular complications.
OBJECTIVES The pathogenesis of systemic sclerosis (SSc) includes vasculopathy with endothelial dysfunction. The aim of this study was to investigate endothelium-dependent, flow-mediated dilatationExpand
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Prolactin and Autoimmunity
Evidence points to an association of prolactin to autoimmune diseases. We examined the correlation between hyperprolactinemia and disease manifestations and activity in a large patient cohort. Age-Expand
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Evaluation of Tear Osmolarity in Non-Sjögren and Sjögren Syndrome Dry Eye Patients With the TearLab System
Purpose: To evaluate tear osmolarity with the recently introduced TearLab system (TearLab Corporation, San Diego, CA) in patients with non-Sjögren syndrome dry eye (NSSDE) and Sjögren syndrome dryExpand
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Hyperferritinemia is Associated with Serologic Antiphospholipid Syndrome in SLE Patients
Ferritin may play a direct role on the immune system. We sought to determine if elevated levels of ferritin in lupus patients correlate with disease activity and organ involvement in a large cohort.Expand
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Rho-associated kinases are crucial for myofibroblast differentiation and production of extracellular matrix in scleroderma fibroblasts.
OBJECTIVE Rho-associated kinases (Rock) are the major cellular mediators of Rho GTPases and play an important role in the organization of the actin cytoskeleton. Inhibitors of Rock are currentlyExpand
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Effects of adalimumab treatment on vascular disease associated with early rheumatoid arthritis.
BACKGROUND Increased cardiovascular morbidity has become a leading cause of mortality in rheumatoid arthritis (RA). Tumor necrosis factor-alpha (TNFa) inhibitors may influence flow-mediatedExpand
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Plasma Homocysteine Levels, The Prevalence of Methylenetetrahydrofolate Reductase Gene C677T Polymorphism and Macrovascular Disorders in Systemic Sclerosis: Risk Factors for Accelerated Macrovascular
The purpose of this study was to investigate plasma homocysteine (Hcy) levels in patients with systemic sclerosis (SSc) and to study the association between plasma Hcy, C677T polymorphism ofExpand
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