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Genetic effects on age-dependent onset and islet cell autoantibody markers in type 1 diabetes.
Age-dependent associations between type 1 diabetes risk genes HLA, INS VNTR, and CTLA-4 and autoantibodies to GAD65 (GADAs), ICA512/IA-2, insulin, and islet cells were determined by logistic… Expand
The incidence of retinopathy 10 years after diagnosis in young adult people with diabetes: results from the nationwide population-based Diabetes Incidence Study in Sweden (DISS).
OBJECTIVE To estimate the prevalence and severity of diabetic retinopathy (DR) 10 years after diagnosis in a nationwide population-based cohort study of young adult diabetic patients in Sweden. … Expand
The incidence of Type I diabetes has not increased but shifted to a younger age at diagnosis in the 0–34 years group in Sweden 1983 to 1998
- A. Pundziute-Lyckå, G. Dahlquist, +8 authors and the Swedish Childhood Diabetes Study Group
- 8 May 2002
AbstractAims/hypothesis. To analyse the incidence of Type I (insulin-dependent) diabetes mellitus in the 0–34 years age group in Sweden 1983–1998. Methods. Incidence and cumulative incidence per 100… Expand
A 12-year prospective study of the relationship between islet antibodies and beta-cell function at and after the diagnosis in patients with adult-onset diabetes.
To clarify the relationships between islet antibodies (islet cell antibody [ICA], GAD antibody [GADA], and IA-2 antibody [IA-2A]) versus the progression of beta-cell dysfunction, we have followed a… Expand
Latent autoimmune diabetes in adults: definition, prevalence, beta-cell function, and treatment.
Latent autoimmune diabetes in adults (LADA) is a disorder in which, despite the presence of islet antibodies at diagnosis of diabetes, the progression of autoimmune beta-cell failure is slow. LADA… Expand
Incidence, prevalence, and mortality of diabetes in a large population. A report from the Skaraborg Diabetes Registry.
OBJECTIVE Our objective was to analyze the prevalence, incidence, and mortality of diabetes in a population of 280,539 inhabitants. RESEARCH DESIGN AND METHODS The incidence, prevalence, and deaths… Expand
Insulin and glucagon secretion in patients with slowly progressing autoimmune diabetes (LADA).
To metabolically characterize patients with slowly progressing autoimmune diabetes (LADA) of short duration we measured insulin, C peptide, and glucagon responses to glucose and arginine at three… Expand
Measurement of hemoglobin A1c by a new liquid-chromatographic assay: methodology, clinical utility, and relation to glucose tolerance evaluated.
- J. Jeppsson, P. Jerntorp, G. Sundkvist, H. Englund, V. Nylund
- Chemistry, Medicine
- Clinical chemistry
- 1 October 1986
A chromatographic method for determining glycated hemoglobin (Hb A1c) by use of a new monodisperse cation-exchanger has been investigated. Hb A1c was separated from other "minor hemoglobins": Hb F,… Expand
Glutamate decarboxylase-, insulin-, and islet cell-antibodies and HLA typing to detect diabetes in a general population-based study of Swedish children.
- W. Hagopian, C. Sanjeevi, +6 authors Å. Lernmark
- The Journal of clinical investigation
- 1 April 1995
Most autoimmune diabetes occurs in those without a diabetic relative, but few cases are identifiable prospectively. To model general population prediction, 491 consecutive newly diabetic children… Expand
Gender differences and temporal variation in the incidence of type 1 diabetes: results of 8012 cases in the nationwide Diabetes Incidence Study in Sweden 1983–2002
Objectives. To establish the gender difference amongst newly diagnosed type 1 diabetic patients aged 15–34 years, considering age at diagnosis, temporal trend and seasonal variation at time of… Expand