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Genetic effects on age-dependent onset and islet cell autoantibody markers in type 1 diabetes.
Age-dependent associations between type 1 diabetes risk genes HLA, INS VNTR, and CTLA-4 and autoantibodies to GAD65 (GADAs), ICA512/IA-2, insulin, and islet cells were determined by logisticExpand
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The incidence of retinopathy 10 years after diagnosis in young adult people with diabetes: results from the nationwide population-based Diabetes Incidence Study in Sweden (DISS).
OBJECTIVE To estimate the prevalence and severity of diabetic retinopathy (DR) 10 years after diagnosis in a nationwide population-based cohort study of young adult diabetic patients in Sweden. Expand
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  • Open Access
The incidence of Type I diabetes has not increased but shifted to a younger age at diagnosis in the 0–34 years group in Sweden 1983 to 1998
AbstractAims/hypothesis. To analyse the incidence of Type I (insulin-dependent) diabetes mellitus in the 0–34 years age group in Sweden 1983–1998. Methods. Incidence and cumulative incidence per 100Expand
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A 12-year prospective study of the relationship between islet antibodies and beta-cell function at and after the diagnosis in patients with adult-onset diabetes.
To clarify the relationships between islet antibodies (islet cell antibody [ICA], GAD antibody [GADA], and IA-2 antibody [IA-2A]) versus the progression of beta-cell dysfunction, we have followed aExpand
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  • Open Access
Latent autoimmune diabetes in adults: definition, prevalence, beta-cell function, and treatment.
Latent autoimmune diabetes in adults (LADA) is a disorder in which, despite the presence of islet antibodies at diagnosis of diabetes, the progression of autoimmune beta-cell failure is slow. LADAExpand
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Incidence, prevalence, and mortality of diabetes in a large population. A report from the Skaraborg Diabetes Registry.
OBJECTIVE Our objective was to analyze the prevalence, incidence, and mortality of diabetes in a population of 280,539 inhabitants. RESEARCH DESIGN AND METHODS The incidence, prevalence, and deathsExpand
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Insulin and glucagon secretion in patients with slowly progressing autoimmune diabetes (LADA).
To metabolically characterize patients with slowly progressing autoimmune diabetes (LADA) of short duration we measured insulin, C peptide, and glucagon responses to glucose and arginine at threeExpand
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Measurement of hemoglobin A1c by a new liquid-chromatographic assay: methodology, clinical utility, and relation to glucose tolerance evaluated.
A chromatographic method for determining glycated hemoglobin (Hb A1c) by use of a new monodisperse cation-exchanger has been investigated. Hb A1c was separated from other "minor hemoglobins": Hb F,Expand
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  • Open Access
Glutamate decarboxylase-, insulin-, and islet cell-antibodies and HLA typing to detect diabetes in a general population-based study of Swedish children.
Most autoimmune diabetes occurs in those without a diabetic relative, but few cases are identifiable prospectively. To model general population prediction, 491 consecutive newly diabetic childrenExpand
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Gender differences and temporal variation in the incidence of type 1 diabetes: results of 8012 cases in the nationwide Diabetes Incidence Study in Sweden 1983–2002
Objectives.  To establish the gender difference amongst newly diagnosed type 1 diabetic patients aged 15–34 years, considering age at diagnosis, temporal trend and seasonal variation at time ofExpand
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