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ImmunoPET/MR imaging allows specific detection of Aspergillus fumigatus lung infection in vivo
Significance Invasive pulmonary aspergillosis (IPA) is a frequently fatal lung disease of immunocompromised patients, and is being increasingly reported in individuals with underlying respiratoryExpand
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Remote‐loading of liposomes with manganese‐52 and in vivo evaluation of the stabilities of 52Mn‐DOTA and 64Cu‐DOTA using radiolabelled liposomes and PET imaging
Abstract Liposomes are nanoparticles used in drug delivery that distribute over several days in humans and larger animals. Radiolabeling with long‐lived positron emission tomography (PET)Expand
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Positron emission tomography imaging of CD105 expression with 89Zr-Df-TRC105
PurposeHigh tumor microvessel density correlates with a poor prognosis in multiple solid tumor types. The clinical gold standard for assessing microvessel density is CD105 immunohistochemistry onExpand
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89Zr radiochemistry for positron emission tomography.
The positron emitting isotope (89)Zr is an ideal radionuclide for use in positron emission tomography (PET) imaging with monoclonal antibodies (mAbs). This article reviews the cyclotron physics ofExpand
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Multimodality imaging of breast cancer experimental lung metastasis with bioluminescence and a monoclonal antibody dual-labeled with 89Zr and IRDye 800CW.
  • Hao Hong, Yin Zhang, +8 authors W. Cai
  • Medicine
  • Molecular pharmaceutics
  • 1 May 2012
Metastatic breast cancer is incurable. The goal of this study was to develop a positron emission tomography (PET)/near-infrared fluorescent (NIRF) probe for imaging CD105 expression in breast cancerExpand
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Exploiting the Metal-Chelating Properties of the Drug Cargo for In Vivo Positron Emission Tomography Imaging of Liposomal Nanomedicines
The clinical value of current and future nanomedicines can be improved by introducing patient selection strategies based on noninvasive sensitive whole-body imaging techniques such as positronExpand
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HaloTag: a novel reporter gene for positron emission tomography.
Among the many molecular imaging techniques, reporter gene imaging has been a dynamic area of research. The HaloTag protein is a modified haloalkane dehalogenase which was designed to covalently bindExpand
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Radiomanganese PET Detects Changes in Functional β-Cell Mass in Mouse Models of Diabetes
The noninvasive measurement of functional β-cell mass would be clinically valuable for monitoring the progression of type 1 and type 2 diabetes as well as the viability of transplantedExpand
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Mouse Positron Emission Tomography Study of the Biodistribution of Gold Nanoparticles with Different Surface Coatings Using Embedded Copper-64.
By taking advantage of the ability of 64Cu to bind nonspecifically to gold surfaces, we have developed a methodology to embed this radionuclide inside gold nanoparticles (AuNPs). 64Cu enables the inExpand
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Very high specific activity ⁶⁶/⁶⁸Ga from zinc targets for PET.
This work describes the production of very high specific activity (66/68)Ga from (nat)Zn(p,n) and (66)Zn(p,n) using proton irradiations between 7 and 16 MeV, with emphasis on (66)Ga for use withExpand
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