G. Sedmak

Publications38
h-index14
Citations2,135
Highly Influential Citations161
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Spatiotemporal transcriptome of the human brain
Brain development and function depend on the precise regulation of gene expression. However, our understanding of the complexity and dynamics of the transcriptome of the human brain is incomplete.… Expand
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Temporal Specification and Bilaterality of Human Neocortical Topographic Gene Expression
Transcriptional events involved in the development of human cerebral neocortex are poorly understood. Here, we analyzed the temporal dynamics and laterality of gene expression in human and macaque… Expand
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Perinatal and early postnatal reorganization of the subplate and related cellular compartments in the human cerebral wall as revealed by histological and MRI approaches
We analyzed the developmental history of the subplate and related cellular compartments of the prenatal and early postnatal human cerebrum by combining postmortem histological analysis with in vivo… Expand
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Coupling diffusion imaging with histological and gene expression analysis to examine the dynamics of cortical areas across the fetal period of human brain development.
  • Hao Huang, Tina Jeon, +8 authors S. Mori
  • Biology, Medicine
  • Cerebral cortex
  • 1 November 2013
As a prominent component of the human fetal brain, the structure of the cerebral wall is characterized by its laminar organization which includes the radial glial scaffold during fetal development.… Expand
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Developmental history of the subplate zone, subplate neurons and interstitial white matter neurons: relevance for schizophrenia
The subplate zone is a transient cytoarchitectonic compartment of the fetal telencephalic wall and contains a population of subplate neurons which are the main neurons of the fetal neocortex and play… Expand
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The significance of the subplate for evolution and developmental plasticity of the human brain
The human life-history is characterized by long development and introduction of new developmental stages, such as childhood and adolescence. The developing brain had important role in these… Expand
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Developmental Expression Patterns of KCC2 and Functionally Associated Molecules in the Human Brain.
Work on rodents demonstrated that steep upregulation of KCC2, a neuron-specific Cl- extruder of cation-chloride cotransporter (CCC) family, commences in supraspinal structures at around birth,… Expand
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Populations of subplate and interstitial neurons in fetal and adult human telencephalon
In the adult human telencephalon, subcortical (gyral) white matter contains a special population of interstitial neurons considered to be surviving descendants of fetal subplate neurons [ Kostovic &… Expand
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The total number of white matter interstitial neurons in the human brain
In the adult human brain, the interstitial neurons (WMIN) of the subcortical white matter are the surviving remnants of the fetal subplate zone. It has been suggested that they perform certain… Expand
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Early history of subplate and interstitial neurons: from Theodor Meynert (1867) to the discovery of the subplate zone (1974)
In this historical review, we trace the early history of research on the fetal subplate zone, subplate neurons and interstitial neurons in the white matter of the adult nervous system. We arrive at… Expand
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