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Definition, assessment and treatment of wheezing disorders in preschool children: an evidence-based approach

Large well-designed randomised controlled trials with clear descriptions of patients are needed to improve the present recommendations on the treatment of these common syndromes.
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Epidemiology and clinical features of Mycoplasma pneumoniae infection in children.

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Dissociation between airway inflammation and airway hyperresponsiveness in allergic asthma.

It is suggested that other factors (e.g., airway wall remodeling or autonomic dysfunction) may be responsible for most of the interindividual variability of airway responsiveness in asthma.
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Prevalence of respiratory syncytial virus infection in Italian infants hospitalized for acute lower respiratory tract infections, and association between respiratory syncytial virus infection risk…

This study was designed to collect data on the prevalence of respiratory syncytial virus (RSV) infection in Italy in infants hospitalized for lower respiratory tract infections, and to evaluate which…
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Bronchoalveolar lavage in children. ERS Task Force on bronchoalveolar lavage in children. European Respiratory Society.

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Inter-society consensus document on treatment and prevention of bronchiolitis in newborns and infants

Pharmacological prophylaxis with palivizumab for RSV bronchiolitis is indicated in specific categories of children at risk during the epidemic period, and may correlate with an increased incidence of recurrent wheezing in pre-schooled children and with asthma at school age.
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Infantile respiratory syncytial virus and human rhinovirus infections: respective role in inception and persistence of wheezing

This review attempts to juxtapose the separate profiles and prototypes of pathogenenetic mechanisms represented by the two most common amongst such viruses: respiratory syncytial virus (RSV) and human rhinovirus (HRV).
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Human bronchial fibroblasts exhibit a mesenchymal stem cell phenotype and multilineage differentiating potentialities

C cultured human adult bronchial fibroblast-like cells (Br) were able to differentiate along the three adipogenic, osteogenic and chondrogenic mesenchymal pathways when cultured under appropriate inducible conditions, indicating that MSCs are present in human adult lung.
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Differences and similarities between SARS-CoV and SARS-CoV-2: spike receptor-binding domain recognition and host cell infection with support of cellular serine proteases

The current state of art about the differences and similarities between the pathogenesis of the two coronaviruses, focusing on receptor binding domain, host cell entry and protease activation, may provide insight into possible intervention strategies to fight the pandemic.
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Clinical, physiologic, and roentgenographic changes after pneumonectomy in a boy with Macleod/Swyer‐James syndrome and bronchiectasis

An 11‐year‐old patient with Macleod/Swyer‐James syndrome and bronchiectasis resulting in severe recurrent bronchopulmonary infections is described.
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