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Modification of radiation‐induced acute oral mucositis in the rat
Curcumin and other components of compound A appeared to be effective in the prevention of radiation‐induced oral mucositis, however, the overall effect observed with the combination drug (compound A) appeared greater than additive. Expand
Comparative assessment of single-dose and fractionated boron neutron capture therapy.
The effects of fractionating boron neutron capture therapy (BNCT) were evaluated in the intracerebral rat 9L gliosarcoma and rat spinal cord models using the Brookhaven Medical Research ReactorExpand
Amelioration of both early and late radiation-induced damage to pig skin by essential fatty acids.
Essential fatty acids can modulate normal tissue reactions when given over the time when radiation damage is normally expressed, and suggest that a > or = 10% higher dose is required to produce the same level of normal tissue injury. Expand
The modulation of radiation-induced damage to pig skin by essential fatty acids.
So-1100 may represent a safe and valuable method of increasing the therapeutic gain in radiotherapy by modulating radiation-induced normal tissue injury and late skin damage was reduced with So-1100. Expand
Boron neutron capture therapy: long-term effects on the skin and spinal cord of the rat.
Findings indicate that the central nervous system has a high tolerance to BNCT-type radiation using BSH as the neutron capture agent, and this model, the rat spinal cord, was used. Expand
Modulation of the cell kinetics of pig skin by the topical application of evening primrose oil or Lioxasol
The daily topical application of two compounds, a cream containing 10% evening primrose oil (EPO) and Lioxasol (a compound used clinically to treat radiation burns), resulted in increased cellExpand
How valid is the assumption of equal effect per fraction?
The findings were not in keeping with values predicted based on the assumption of equal effect per fraction and could not be explained by the use of a single alpha/beta ratio in the LQ-model. Expand
An effect of neoplasms on glutamic acid metabolism in the host.
Two strains of rats in which tumors were produced by methylcholanthrene or by implantation have shown increased levels of free glutamic acid in the blood plasma and there is a significant increase in aspartic-glutamic transaminase in the livers of tumor-bearing rats. Expand
Trophic effects of essential fatty acids on pig skin
The daily oral administration of 3 ml of two oils (So‐5407 and So‐1129) containing essential fatty acids (EFAs) for 16 weeks resulted in a transient increase in cell proliferative activity in theExpand
The effect of rat liver carcinomas, growing in the yolk sacs of chick embryos, on the free glutamic acid and glutamine content of the eggs.
Estimations have shown a definite rise in the free glutamic acid concentration of eggs with tumors, which was apparent in 7–9 days following tumor injection, and Tumor tissue was found to have a lower concentration of free glutamate acid than the egg alone. Expand