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Cloning, characterization, and gene organization of K-Cl cotransporter from pig and human kidney and C. elegans.
We isolated and characterized the cDNAs for the human, pig, and Caenorhabditis elegansK-Cl cotransporters. The pig and human homologs are 94% identical and contain 1,085 and 1,086 amino acids,Expand
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Molecular characterization of two novel transporters from human and mouse kidney and from LLC-PK1 cells reveals a novel conserved family that is homologous to bacterial and Aspergillus nucleobase
Nucleobase transport is important for the metabolism of nucleic acids and antiviral and antineoplastic drugs. This transport has been functionally described in several mammalian cells but has notExpand
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Clinical and genetic correlates of serum aldosterone in the community: the Framingham Heart Study.
BACKGROUND We investigated the environmental and genetic sources of interindividual variability in serum aldosterone level in a large, community-based sample. METHODS We examined the relation ofExpand
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Acute interstitial nephritis associated with moxifloxacin use.
BACKGROUND Moxifloxacin is a fluoroquinolone antimicrobial agent with proven efficacy against community-acquired respiratory pathogens. Common adverse effects associated with its use includeExpand
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Cloning, characterization, and gene organization of K-Cl cotransporter from pig and human kidney and C. elegans.
We isolated and characterized the cDNAs for the human, pig, and Caenorhabditis elegans K-Cl cotransporters. The pig and human homologs are 94% identical and contain 1,085 and 1,086 amino acids,Expand