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Hypoxic survival strategies in two fishes: extreme anoxia tolerance in the North European crucian carp and natural hypoxic preconditioning in a coral-reef shark
TLDR
The present knowledge of two fishes that have evolved to survive hypoxia under very different circumstances, the crucian carp and the epaulette shark, is summarized. Expand
Exposure to hypoxia primes the respiratory and metabolic responses of the epaulette shark to progressive hypoxia.
TLDR
Interestingly, hypoxia tolerance was dynamic because hypoxic pre-conditioning lowered the VO(2) of the epaulette shark by 29%, which resulted in a significantly reduced [O(2)](crit) (1.7 mg O( 2) l(-1)), revealing that hypoxicPre- conditioning elicits an enhanced physiological response to hypoxIA. Expand
A radical approach to beating hypoxia: depressed free radical release from heart fibres of the hypoxia-tolerant epaulette shark (Hemiscyllum ocellatum)
TLDR
Overall, the epaulette shark ventricular mitochondria showed greater oxidative phosphorylation stability and lower reactive species outputs with hypoxic exposure, and this may protect cardiac bioenergetic function in hypoxic tropical waters. Expand
Hypoxia tolerance in elasmobranchs. I. Critical oxygen tension as a measure of blood oxygen transport during hypoxia exposure
TLDR
It is suggested that Pcrit can predict Hb–O2 saturation and CaO2 during hypoxia exposure, with a lower Pcrit being associated with greater O2 supply at a given PwO2 and consequently betterHypoxia tolerance, and Pcrit is a valuable predictor of environmental hypoxIA tolerance. Expand
Could thermal sensitivity of mitochondria determine species distribution in a changing climate?
TLDR
The present study confirmed that cardiac mitochondrial dysfunction contributes to heat stress-induced HF in two additional wrasses that occupy cold temperate (Notolabrus fucicola) and tropical habitats, and supported the view that species distribution may be related to the thermal limits of mitochondrial stability and function. Expand
Molecular evolution of the metazoan PHD-HIF oxygen-sensing system.
TLDR
An unexpected diversity of PHD genes and HIF alpha sequence characteristics in invertebrates is revealed, suggesting that the simple oxygen-sensing systems of Caenorhabditis and Drosophila may not be typical of other invertebrate bilaterians. Expand
Hypoxia Tolerance in the Epaulette Shark (Hemiscyllium ocellatum)
TLDR
It is concluded that the epaulette shark is tolerant to both mild Hypoxia and to cyclic exposure to extreme hypoxia, suggesting that it has a well-developed capacity for anaerobic metabolism. Expand
The role of adenosine in the anoxic survival of the epaulette shark, Hemiscyllium ocellatum.
TLDR
Results suggest that adenosine receptor activation had a pre-emptive role in maintaining brain ATP levels during anoxia, which is among the few vertebrates that can tolerate extreme hypoxia for prolonged periods and, as shown here, anoxIA. Expand
Hypoxia tolerance in elasmobranchs. II. Cardiovascular function and tissue metabolic responses during progressive and relative hypoxia exposures
TLDR
Lower tissue [lactate] accumulation in epaulette sharks than in shovelnose rays during relative hypoxia exposure suggests that enhanced extra-cardiac metabolic depression occurs in the former species, potentially explaining the greater hypoxic cardiovascular function of epaulett sharks. Expand
Transcriptional responses to hypoxia are enhanced by recurrent hypoxia (hypoxic preconditioning) in the epaulette shark.
TLDR
It is discovered that hypoxia preconditioning amplifies transcriptional responses compared with animals that experienced a single hypoxic bout, which suggests that in a single short-term hyp toxic bout, the responses to low oxygen are regulated at the level of pre-existing proteins or translational and posttranslational machinery. Expand
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