• Publications
  • Influence
Chronic kidney disease after nephrectomy in patients with renal cortical tumours: a retrospective cohort study.
BACKGROUND Chronic kidney disease is a graded and independent risk factor for substantial comorbidity and death. We aimed to examine new onset of chronic kidney disease in patients with small, renalExpand
  • 1,282
  • 37
Targeting chromatin binding regulation of constitutively active AR variants to overcome prostate cancer resistance to endocrine-based therapies
Androgen receptor (AR) variants (AR-Vs) expressed in prostate cancer (PCa) lack the AR ligand binding domain (LBD) and function as constitutively active transcription factors. AR-V expression inExpand
  • 109
  • 12
Renal function outcomes in patients treated for renal masses smaller than 4 cm by ablative and extirpative techniques.
PURPOSE We examined the effect of radical nephrectomy, partial nephrectomy and radio frequency ablation on renal function in patients with stage T1a renal masses. MATERIALS AND METHODS A total ofExpand
  • 201
  • 10
The impact of targeted molecular therapies on the level of renal cell carcinoma vena caval tumor thrombus.
BACKGROUND Targeted molecular therapies (TMTs) previously have demonstrated oncologic activity in renal cell carcinoma (RCC) by reducing the size of primary tumors and metastases. OBJECTIVE ToExpand
  • 123
  • 8
Percutaneous management of calculi within horseshoe kidneys.
PURPOSE Percutaneous treatment of patients with calculi in a horseshoe kidney can be challenging due to the altered anatomical relationship in the retroperitoneum. Therefore, we performed aExpand
  • 121
  • 7
Ureteral access sheath provides protection against elevated renal pressures during routine flexible ureteroscopic stone manipulation.
BACKGROUND AND PURPOSE New-generation flexible ureteroscopes allow the management of proximal ureteral and intrarenal pathology with high success rates, including complete removal of ureteral andExpand
  • 209
  • 6
Truncation and constitutive activation of the androgen receptor by diverse genomic rearrangements in prostate cancer
Molecularly targeted therapies for advanced prostate cancer include castration modalities that suppress ligand-dependent transcriptional activity of the androgen receptor (AR). However, persistent ARExpand
  • 75
  • 6
Dual roles of PARP-1 promote cancer growth and progression.
UNLABELLED PARP-1 is an abundant nuclear enzyme that modifies substrates by poly(ADP-ribose)-ylation. PARP-1 has well-described functions in DNA damage repair and also functions as a context-specificExpand
  • 207
  • 5
Incidence of benign lesions for clinically localized renal masses smaller than 7 cm in radiological diameter: influence of sex.
PURPOSE We determined the incidence of benign renal lesions in patients undergoing definitive surgery for localized renal masses 7 cm or less in maximum radiological diameter, and assessedExpand
  • 128
  • 5
Outcomes following erosions of the artificial urinary sphincter.
PURPOSE Artificial urinary sphincter urethral cuff erosion occurs in up to 5.0% of cases, presenting a complex management problem. We examine our experience with the eroded AUS, relating toExpand
  • 105
  • 5