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The validation of Calophyllum brasiliense (“guanandi”) uses in Brazilian traditional medicine as analgesic by in vivo antinociceptive evaluation and its chemical analysis
- L. Klein-Júnior, Daniele Zambiasi, G. R. Salgado, F. Delle Monache, V. C. Filho, Fátima de Campos Buzzi
- BiologyNaunyn-Schmiedeberg's Archives of Pharmacology
- 8 April 2017
TRPV1 channels play an important role in the mechanism of action of the chloroform fraction of C. brasiliense (CFCB) roots and 1,2-dimethoxyxanthone largely contributes to the antinociceptive effect of CFCB.