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Dendritic and synaptic pathology in experimental autoimmune encephalomyelitis.
Evidence has shown that excitotoxicity may contribute to the loss of central nervous system axons and oligodendrocytes in multiple sclerosis and experimental autoimmune encephalomyelitis (EAE).Expand
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Ionotropic glutamate receptor expression in human white matter
Glutamate is the key excitatory neurotransmitter of the central nervous system (CNS). Its role in human grey matter transmission is well understood, but this is less clear in white matter (WM).Expand
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Axonal cytoskeleton changes in experimental optic neuritis
Axonal loss and degeneration in multiple sclerosis (MS) and experimental allergic encephalomyelitis (EAE) have been suggested by brain imaging, pathological and axonal transport studies. FurtherExpand
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Association of &agr;-Synuclein Immunoreactivity With Inflammatory Activity in Multiple Sclerosis Lesions
Multiple sclerosis (MS) has neurodegenerative features including neuronal and axonal loss and widespread atrophy of the brain and spinal cord. The cause of this neurodegeneration has been largelyExpand
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Imaging Mechanisms of Disease Progression in Multiple Sclerosis: Beyond Brain Atrophy
Clinicians involved with different aspects of the care of persons with multiple sclerosis (MS) and scientists with expertise on clinical and imaging techniques convened in Dallas, TX, USA on FebruaryExpand
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Complement and Humoral Adaptive Immunity in the Human Choroid Plexus: Roles for Stromal Concretions, Basement Membranes, and Epithelium
The choroid plexus (CP) provides a barrier to entry of toxic molecules from the blood into the brain and transports vital molecules into the cerebrospinal fluid. While a great deal is known about CPExpand
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Heredity, Growth, and the Dento-Facial Complex*
Abstract No Abstract Available. * Rackham Research Project Number Rj4 of the Horace H. Rackham School for Graduate Studies, University of Michigan, Ann Arbor, Michigan. Read before the ChicagoExpand
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Expression of CD1d by astrocytes corresponds with relative activity in multiple sclerosis lesions
The CD1 protein family present lipid antigens to the immune system. CD1d has been observed in the CNS of MS patients, yet no studies have quantitatively characterized this expression and related itExpand
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