• Publications
  • Influence
Transglutaminase activity and Nϵ(γ‐glutamyl) lysine isopeptide levels during cell growth: An enzymic and immunological study
TLDR
Compared with other reported methods for measuring isopeptides, this immunohistological approach permits the localization and at least the semi‐quantitative determination of Nϵ(γ glutamyl) lysine in cells in situ.
gamma-Glutamyltranspeptidase activity in human breast lesions: an unfavourable prognostic sign.
TLDR
In biopsies from normal tissue and benign lesions, labelling was very intense in lumina and in the apical pole of the cells lining the lumina whilst in the cytoplasm it was slightly positive.
Red blood cell polyamines in mice bearing the lewis lung carcinoma (3ll) and in patients with bronchopulmonary cancers
TLDR
Clinical use of these molecules as tumor markers depends on an understanding of polyamine distribution within blood, and high levels of RBC polyamine are observed in cases of squamous‐cell carcinoma or anaplastic cancer, and not in Cases of adenocarcinoma.
Differential expression of isopeptide bonds Nϵ(γ‐glutamyl) lysine in benign and malignant human breast lesions: An immunohistochemical study
TLDR
Nϵ(γ‐glutamyl) lysine isopeptide bonds were detected situ in histological sections from benign and malignant human breast tissue using the monoclonal antibody (MAb) 8 ID Ic2 and staining was restricted to the nuclei.
Diamine and polyamine oxidase activities in normal and transformed cells
TLDR
Differences of about the same order of magnitude are observed between transformed human cells HeLa, HEp2 and normal human fibroblasts, in chicken cells between normal myeloblasts and leukaemic myELoblasts, and in rats between biopsy material from normal mammary tissue and 9,10-dimethylbenz[ a ]anthracene-induced mammary tumours.
...
...