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Satiety factor oleoylethanolamide recruits the brain histaminergic system to inhibit food intake
Significance Several endogenous molecules contribute to the building of a complex network of neural and hormonal signals that align food intake and energy expenditure. Cerebral histamine works as aExpand
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Carbonic anhydrase activation enhances object recognition memory in mice through phosphorylation of the extracellular signal-regulated kinase in the cortex and the hippocampus
ABSTRACT Rats injected with by d‐phenylalanine, a carbonic anhydrase (CA) activator, enhanced spatial learning, whereas rats given acetazolamide, a CA inhibitor, exhibited impairments of fear memoryExpand
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TLC Fingerprint of Flavonoids and Saponins from Passiflora Species
Abstract Several Passiflora species, known in Brazil as maracujás, are used as flavour and as juice in food industries, whereas passionflower extract has an ancient tradition in folk medicine as aExpand
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Histamine neurons in the tuberomamillary nucleus: a whole center or distinct subpopulations?
Histamine axons originate from a single source, the tuberomamillary nucleus (TMN) of the posterior hypothalamus, to innervate almost all central nervous system (CNS) regions. This feature, a compactExpand
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Histamine mediates behavioural and metabolic effects of 3‐iodothyroacetic acid, an endogenous end product of thyroid hormone metabolism
3‐Iodothyroacetic acid (TA1) is an end product of thyroid hormone metabolism. So far, it is not known if TA1 is present in mouse brain and if it has any pharmacological effects.
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Constituents from leaves of Quillaja brasiliensis
A new abietane diterpene, the 19-O-β-d-glucopyranoside of 16-hydroxylambertic acid was isolated from the leaves of Quillaja brasiliensis together with a known prosapogeninExpand
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Central mechanisms mediating the hypophagic effects of oleoylethanolamide and N-acylphosphatidylethanolamines: different lipid signals?
The spread of “obesity epidemic” and the poor efficacy of many anti-obesity therapies in the long-term highlight the need to develop novel efficacious therapy. This necessity stimulates a largeExpand
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The histaminergic system as a target for the prevention of obesity and metabolic syndrome
The control of food intake and body weight is very complex. Key factors driving eating behavior are hunger and satiety that are controlled by an interplay of several central and peripheralExpand
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Histamine in the basolateral amygdala promotes inhibitory avoidance learning independently of hippocampus
Significance Integrity of the brain histaminergic system is necessary for long-term memory (LTM) but not short-term memory of step-down inhibitory avoidance (IA). Histamine depletion in hippocampusExpand
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Donepezil, an acetylcholine esterase inhibitor, and ABT-239, a histamine H3 receptor antagonist/inverse agonist, require the integrity of brain histamine system to exert biochemical and procognitive
Histaminergic H3 receptors (H3R) antagonists enhance cognition in preclinical models and modulate neurotransmission, in particular acetylcholine (ACh) release in the cortex and hippocampus, two brainExpand
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