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Agitated "unipolar" depression re-conceptualized as a depressive mixed state: implications for the antidepressant-suicide controversy.
TLDR
Agitated depression emerges as a distinct affective syndrome with weight loss, pressure of speech, racing thoughts and suicidal ideation, which overall accord with classical German concepts of agitated depression as a mixed state. Expand
The International Society for Bipolar Disorders (ISBD) task force report on antidepressant use in bipolar disorders.
TLDR
A consensus was reached on 12 statements on the use of antidepressants in bipolar disorder, and antidepressants should be prescribed only as an adjunct to mood-stabilizing medications. Expand
The clinical impact of bipolar and unipolar affective comorbidity on obsessive-compulsive disorder.
TLDR
It is submitted that the presence of major depression in OCD is incidental, as OCD in such cases dominates the course and dictates treatment choice, and bipolarity should take precedence in diagnosis, course and treatment considerations. Expand
Prevalence and characteristics of undiagnosed bipolar disorders in patients with a major depressive episode: the BRIDGE study.
TLDR
Family history, illness course, and clinical status, in addition to DSM-IV-TR criteria, may provide useful information for physicians when assessing evidence of bipolarity in patients with major depressive episodes, and is recommended before deciding on treatment. Expand
The high prevalence of "soft" bipolar (II) features in atypical depression.
TLDR
The data suggest that the "atypicality" of depression is favored by affective temperamental dysregulation and anxiety comorbidity, clinically manifesting in a mood disorder subtype that is preponderantly in the realm of bipolar II. Expand
Polarity of the first episode, clinical characteristics, and course of manic depressive illness: a systematic retrospective investigation of 320 bipolar I patients.
TLDR
Overall, the data support the existence of distinct longitudinal patterns within bipolar I disorder, which in turn appear correlated with the polarity at onset, and suggest rapid cycling and mixed states emerge as distinct psychopathologic processes. Expand
Gender-related differences in body dysmorphic disorder (dysmorphophobia).
TLDR
It is hypothesized that gender would differentially influence the localization of the preoccupations as well as the extent and type of comorbidity with other psychiatric disorders, and BDD does appear to be an autonomous syndrome, and gender tends to influence the nature and extent of this comorebidity. Expand
Obsessive–compulsive disorder and body dysmorphic disorder: a comparison of clinical features
TLDR
The co-presence of BDD and OCD features appears to possibly individuate a particularly severe form of the syndrome, with a greater load of psychopathology and functional impairment and a more frequent occurrence of other comorbid mental disorders. Expand
Clinical subtypes of bipolar mixed states: validating a broader European definition in 143 cases.
TLDR
The phenomenology of mixed states is more than the mere superposition of opposite affective symptoms and, in many instances, it represents an expansive-excited phase intrusion into a depressive temperament, and a melancholic episode intruding into a hyperthymic temperament. Expand
Mixed features in patients with a major depressive episode: the BRIDGE-II-MIX study.
TLDR
Depressive mixed state, defined as the presence of 3 or more manic/hypomanic features, was present in around one-third of patients experiencing an MDE, and yielded statistically more robust associations with several illness characteristics of bipolar disorder than did DSM-5 criteria. Expand
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