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Global variation in copy number in the human genome
Copy number variation (CNV) of DNA sequences is functionally significant but has yet to be fully ascertained. We have constructed a first-generation CNV map of the human genome through the study ofExpand
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Diet and the evolution of human amylase gene copy number variation
Starch consumption is a prominent characteristic of agricultural societies and hunter-gatherers in arid environments. In contrast, rainforest and circum-arctic hunter-gatherers and some pastoralistsExpand
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Common deletion polymorphisms in the human genome
The locations and properties of common deletion variants in the human genome are largely unknown. We describe a systematic method for using dense SNP genotype data to discover deletions and itsExpand
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Copy number variation: new insights in genome diversity.
DNA copy number variation has long been associated with specific chromosomal rearrangements and genomic disorders, but its ubiquity in mammalian genomes was not fully realized until recently.Expand
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The fine-scale and complex architecture of human copy-number variation.
Despite considerable excitement over the potential functional significance of copy-number variants (CNVs), we still lack knowledge of the fine-scale architecture of the large majority of CNV regionsExpand
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Hotspots for copy number variation in chimpanzees and humans.
Copy number variation is surprisingly common among humans and can be involved in phenotypic diversity and variable susceptibility to complex diseases, but little is known of the extent of copy numberExpand
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Copy number variation and evolution in humans and chimpanzees.
Copy number variants (CNVs) underlie many aspects of human phenotypic diversity and provide the raw material for gene duplication and gene family expansion. However, our understanding of theirExpand
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Analysis of copy number variation in the rhesus macaque genome identifies candidate loci for evolutionary and human disease studies.
Copy number variants (CNVs) are heritable gains and losses of genomic DNA in normal individuals. While copy number variation is widely studied in humans, our knowledge of CNVs in other mammalianExpand
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Evolution of the human pygmy phenotype.
Small human body size, or the 'pygmy' phenotype, is characteristic of certain African, Southeast Asian and South American populations. The convergent evolution of this phenotype, and its strongExpand
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Dispersals and genetic adaptation of Bantu-speaking populations in Africa and North America
Genetic analysis reveals the complex history of sub-Saharan Africans and African Americans. On the history of Bantu speakers Africans are underrepresented in many surveys of genetic diversity, whichExpand
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