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Proposed Model: Mechanisms of Immunomodulation Induced by Probiotic Bacteria
TLDR
The healthy host is able to elicit a good mucosal immune response against luminal antigens and to maintain a “physiological state of inflammation” in the gut, but it is also capable of responding to invading commensal organisms or pathogens. Expand
The Probiotic Bacterium Lactobacillus casei Induces Activation of the Gut Mucosal Immune System through Innate Immunity
TLDR
The main immune cells activated after oral L. casei administration were those of the innate immune response, with an increase in the specific markers of these cells (CD-206 and TLR-2), with no modification in the number of T cells. Expand
Role of Intestinal Epithelial Cells in Immune Effects Mediated by Gram-Positive Probiotic Bacteria: Involvement of Toll-Like Receptors
TLDR
The small intestine is the place where a major distinction would occur between probiotic LAB and pathogens, cutting across the line that separates IL-6 necessary for B-cell differentiation, from inflammatory levels of IL- 6 for pathogens. Expand
Interference of Lactobacillus plantarum with Pseudomonas aeruginosa in vitro and in infected burns: the potential use of probiotics in wound treatment.
TLDR
Results indicate that L. plantarum and/or its by-products are potential therapeutic agents for the local treatment of P. aeruginosa burn infections. Expand
Interaction of lactic acid bacteria with the gut immune system
TLDR
It is shown that lactic acid bacteria induce distinct mucosal cytokine profiles showing different adjuvant capacity among them, and selection of probiotic strain with immunological properties must be well defined to influence cytokine expression that favour the claimed immune response. Expand
Immune system stimulation by probiotics.
TLDR
The results showed that Lactobacillus casei could prevent enteric infections and stimulate secretory IgA in malnourished animals, but could produce bacteria translocation and Yogurt could inhibit the growth of intestinal carcinoma through increased activity of IgA, T cells, and macrophages. Expand
Effects of the oral administration of the exopolysaccharide produced by Lactobacillus kefiranofaciens on the gut mucosal immunity.
TLDR
It is observed that the exopolysaccharide induced a gut mucosal response and it was able to up and down regulate it for protective immunity, maintaining intestinal homeostasis, enhancing the IgA production at both the small and large intestine level and influencing the systemic immunity through the cytokines released to the circulating blood. Expand
Oral administration of a probiotic Lactobacillus modulates cytokine production and TLR expression improving the immune response against Salmonella enterica serovar Typhimurium infection in mice
TLDR
The oral administration of L. casei CRL 431 induces variations in the cytokine profile and in the TLRs expression previous and also after the challenge with S. Typhimurium, providing an alternative way to reduce the severity of the infection. Expand
Immunomodulating effects of peptidic fractions issued from milk fermented with Lactobacillus helveticus.
TLDR
It is shown that bioactive compounds released in fermented milks contribute to the immunoenhancing and antitumor properties of these products. Expand
Systemic augmentation of the immune response in mice by feeding fermented milks with Lactobacillus casei and Lactobacillus acidophilus.
TLDR
Results suggest that L. casei and L. acidophilus, associated with intestinal mucosae, can influence the level of activation of the immune system, and the possible clinical application of fermented milks as immunopotentiators is discussed. Expand
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