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Polyunsaturated Fatty Acids: Biochemical, Nutritional and Epigenetic Properties
TLDR
This review will focus on recent advances on the essentiality of these molecules and on their interplay in cell physiology, leading to new perspective in different therapeutic fields.
Clinical Trials with Mesenchymal Stem Cells: An Update
TLDR
Clinical trials using MSCs for representative diseases, including hematological disease, graft-versus-host disease, organ transplantation, diabetes, inflammatory diseases, and diseases in the liver, kidney, and lung are analyzed, as well as cardiovascular, bone and cartilage, neurological, and autoimmune diseases.
Cancer and anticancer therapy‐induced modifications on metabolism mediated by carnitine system
TLDR
A more complex approach to mechanisms that underlie tumor growth, which takes into account the altered metabolic pathways in cancer disease, could represent a challenge for the future of cancer research.
Molecular pathways involved in neural in vitro differentiation of marrow stromal stem cells
TLDR
The research indicates that the currently used in vitro differentiation protocols, while they allow the early steps of neural differentiation to take place, are not able to further sustain this process.
Cross-talk between fMLP and Vitronectin Receptors Triggered by Urokinase Receptor-derived SRSRY Peptide*
TLDR
The data indicate that the ability of uPAR to stimulate cell migration and cytoskeletal rearrangements is retained by the SRSRY peptide alone and that it is supported by cross-talk between FPR and αvβ5.
Chitosan-mediated stimulation of macrophage function.
TLDR
The present investigation demonstrates that chitosan has an in vitro stimulatory effect on both macrophage nitric oxide (NO) production and chemotaxis and strengthens the hypothesis that in vivo experiments strengthen this hypothesis.
17‐B estradiol elicits an autocrine leiomyoma cell proliferation: Evidence for a stimulation of protein kinase‐dependent pathway
TLDR
The experiments suggest that growth factor secretion is an initial and integral part of the signaling events mediated by the estradiol receptors, not related, at least in part, to E2 transcriptional modulation.
Carnitine: An osmolyte that plays a metabolic role
TLDR
Examination of the osmolytic properties of carnitine is examined in an attempt to clarify the metabolic functions Carnitine has acquired during evolution.
Skeletal muscle metabolism in physiology and in cancer disease
TLDR
This extremely balanced system is greatly altered by cancer disease that can induce muscle cachexia with significant deleterious consequences and results in muscle wasting and weakness, delaying or preventing ambulation, and rehabilitation in catabolic patients.
17-beta estradiol elicits an autocrine leiomyoma cell proliferation: evidence for a stimulation of protein kinase-dependent pathway.
TLDR
The experiments suggest that growth factor secretion is an initial and integral part of the signaling events mediated by the estradiol receptors, not related, at least in part, to E2 transcriptional modulation.
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