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Antimicrobial and mutagenic properties of organotin(IV) complexes with isatin and N-alkylisatin bisthiocarbonohydrazones.
The organotin(IV) complexes of isatin and N-methylisatin exhibit good antibacterial activity, better than that of the corresponding N-butyl and N -pentylisatin derivatives. Expand
Organotin complexes with pyrrole-2,5-dicarboxaldehyde bis(acylhydrazones). Synthesis, structure, antimicrobial activity and genotoxicity.
None of the ligands or complexes produced DNA-damage in the Bacillus subtilis rec-assay or showed mutagenic activity in the Salmonella-microsome test. Expand
Antimicrobial and mutagenic activity of some carbono- and thiocarbonohydrazone ligands and their copper(II), iron(II) and zinc(II) complexes.
All bisthiocarbono- and carbonohydrazones are devoid of mutagenic properties, with the exception of the compounds derived from 5-nitrofuraldehyde. Expand
Synthesis and antimicrobial activity of new 3-(1-R-3(5)-methyl-4-nitroso-1H-5(3)-pyrazolyl)-5-methylisoxazoles.
A number of new 3-(1-R-3(5)-methyl-4-nitroso-1H-5(3)-pyrazolyl)-5-methylisoxazoles 6a-g (7b-f) were synthesized and tested for antibacterial and antifungal activity. Some of these compounds displayedExpand
Antimicrobial and genotoxic activity of 2,6-diacetylpyridine bis(acylhydrazones) and their complexes with some first transition series metal ions. X-ray crystal structure of a dinuclear copper(II)
The antibacterial and antifungal properties of five 2,6-diacetylpyridine bis(acylhydrazones) and of a series of metal complexes were investigated and the genotoxic properties of the ligands disappeared in the complexes. Expand
X-ray structure determination of mexiprostil, a new gastroprotective 16-methoxy-16-methyl-PGE1 analogue.
Mexiprostil is a new gastroprotective 16-methoxy-16-methyl-PGE1 methyl ester and X-ray diffraction results established that the configuration at C-15 is also R. Expand
Synthesis, structure, antimicrobial, and genotoxic activities of organotin compounds with 2,6-diacetylpyridine nicotinoyl- and isonicotinoylhydrazones.
In all cases the complexes show a reduced antimicrobial activity as compared to that of the corresponding organotin compound, and the genotoxic properties of the ligands, detected in the Ames test, disappear in the complexes. Expand
Synthesis, structure, and biological activity of organotin compounds with di-2-pyridylketone and phenyl(2-pyridyl) ketone 2-aminobenzoylhydrazones.
None of the compounds showed genotoxicity in the Bacillus subtilis rec-assay and in the Salmonella-microsome test, and the in vitro evaluation of antimicrobial properties revealed the strong activity of Sn (C6H5)2(Hdpa)Cl2 and Sn(C6 H5)3Cl(OH2). Expand
Organotin complexes with pyrrole-2-carboxaldehyde monoacylhydrazones. Synthesis, spectroscopic properties, antimicrobial activity, and genotoxicity.
A series of organotin complexes with pyrrole-2-carboxaldehyde 2-hydroxybenzoylhydrazone (H3mfps), H2mfpp, and its complexes are investigated and shown by the Salmonella-microsome assay to be mutagenic substances in the presence of a metabolic activation system. Expand
Tetranuclear copper(II) complexes with polydentate hydrazone ligands : synthesis and X-ray structure
Abstract The synthesis and X-ray crystal structure of two copper(II) complexes, [Cu2(dappc)(OH2)3]2- [Cu2(dappc)(OH2)2(ClO4)]2)6·2H2O (I) (H2dappc=2,6-diacetylpyridineExpand