Share This Author
Depletion of reduced glutathione, ascorbic acid, vitamin E and antioxidant defence enzymes in a healing cutaneous wound.
The results indicate that wounding results in loss of different free radical scavengers both enzymatic and non-enzymatic which either partially or completely recover following healing.
Free radicals and antioxidant status following pylorus ligation induced gastric mucosal injury in rats.
Results obtained have shown alterations in the antioxidant status following ulceration, indicating that free radicals seems to be associated with the pylorus ligation induced ulcers in rats.
Protective action of ursolic acid against chemical induced hepato-toxicity in rats
Ursolic acid isolated from the leaves of Eucalyptus hybrid E. tereticomis showed a dose dependent (5-20 mg/kg) hepatoprotective activity (21-l 00%) in rats against thioacetamide, galactosamine and…
Hepatoprotective activity in the rat of ursolic acid isolated from eucalyptus hybrid
Ursolic acid showed a marked hepatoprotective activity against paracetamol and galactosamine induced hepatotoxicity by reversing the altered values in viability of the isolated hepatocytes and the altered biochemical liver and serum parameters.
Antihepatotoxic and immunostimulant properties of iridoid glycosides of Scrophularia koelzii
The alcoholic extract of the aerial parts of Scrophularia koelzii significantly protected the rat liver against thioacetamide induced toxicity and showed maximum hepatoprotective activity.
Morphine-induced straub tail response: mediated by central mu2-opioid receptor.
Activity of certain fractions of Tribulus terrestris fruits against experimentally induced urolithiasis in rats.
- R. Anand, G. Patnaik, D. K. Kulshreshtha, B. Dhawan
- MedicineIndian journal of experimental biology
- 1 August 1994
An ethanolic extract of the fruits of T. terrestris showed significant dose dependent protection against uroliths induced by glass bead implantation in albino rats, and fractionation lead to decreased activity.
Arnebin-1 accelerates normal and hydrocortisone-induced impaired wound healing.
- G. Sidhu, A. K. Singh, K. Banaudha, J. Gaddipati, G. Patnaik, R. Maheshwari
- Biology, MedicineThe Journal of investigative dermatology
- 1 November 1999
It is suggested that arnebin-1 could be developed as a potent therapeutic agent for wound healing in steroid-impaired wounds because of its role in promoting cell proliferation, migration, and vessel formation and enhancement of wound healing during normal and impaired wound repair.
Role of endothelial-derived reactive oxygen species and nitric oxide in norepinephrine-induced rat aortic ring contractions.
- P. Srivastava, L. G. Hegde, G. Patnaik, M. Dikshit
- Biology, ChemistryPharmacological research
- 1 October 1998
Investigation of endothelial-derived reactive oxygen species and their interaction with nitric oxide during norepinephrine-induced contraction of rat aortic rings indicated the involvement of endothelium-derived hydrogen peroxide, superoxide and hydroxyl radicals in the NE-induced contractions.
Wound healing activity of latex of Euphorbia neriifolia Linn
- A. Rasik, A. Shukla, G. Patnaik, Dhawan Bn, D. K. Kulshrestha, Swayam Prakash Srivastava
- 1 April 1996
The wound healing effect of aqueous extract of the latex of Euphorbia neriifolia was evaluated in guinea pig as evidenced by increase in tensile strength, DNA content, epithelization and angiogenesis.