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Speaking the same language: The World Allergy Organization Subcutaneous Immunotherapy Systemic Reaction Grading System.
TLDR
A uniform classification system for grading SCIT SRs will be helpful in assessing more accurately when epinephrine should be administered, and may prevent the progression of an SR to a more serious life-threatening problem. Expand
Sublingual immunotherapy: World Allergy Organization position paper 2013 update
TLDR
“Raising public awareness about sublingual immunotherapy”, as a need for patients, and strategies to increase awareness of allergen immunotherapy (AIT) among patients, the medical community, all healthcare stakeholders, and public opinion are reported in detail. Expand
Allergic rhinitis and its impact on asthma update: allergen immunotherapy.
TLDR
The clinical efficacy of injection immunotherapy in rhinitis and asthma was confirmed, as well as the safety, provided that recommendations are followed, and current data indicate that sublingual immunotherapy is safe and the rate of adverse reactions is not greater below 5 years of age. Expand
Clonal mast cell disorders in patients with systemic reactions to Hymenoptera stings and increased serum tryptase levels.
TLDR
The concomitant presence of systemic reactions (especially anaphylaxis) after Hymenoptera stings and increased sBT levels strongly suggests that a BM examination is indicated for the diagnosis of clonal MC disease. Expand
Oral Immunotherapy for Egg Allergy: A Double-Blind Placebo-Controlled Study, with Postdesensitization Follow-Up.
TLDR
Egg OIT results in desensitization in almost all subjects, although tolerance was maintained in only 1/3 of them after a 3-month period of withdrawal, whereas in the control group, only 1% remained tolerant. Expand
Efficacy of sublingual immunotherapy in the treatment of allergic rhinitis in pediatric patients 3 to 18 years of age: a meta-analysis of randomized, placebo-controlled, double-blind trials.
TLDR
The results of this meta-analysis showed that,compared with placebo, SLIT with standardized extracts is effective in pediatric patients with allergic rhinitis. Expand
The efficacy of sublingual immunotherapy for house dust mites respiratory allergy: results of a GA²LEN meta‐analysis
TLDR
Investigation of the efficacy of SLIT with house dust mite (HDM) extracts in allergic patients suffering from AR and AA through an updated reassessment of randomized controlled trials suggests that more data are needed, derived from large‐population‐based high quality studies, and corroborated by objective outcomes. Expand
Preventive effects of sublingual immunotherapy in childhood: an open randomized controlled study.
TLDR
In everyday clinical practice, SLIT reduced the onset of new sensitizations and mild persistent asthma and decreased bronchial hyperreactivity in children with respiratory allergy. Expand
Long‐lasting effect of sublingual immunotherapy in children with asthma due to house dust mite: a 10‐year prospective study
Background Subcutaneous immunotherapy for respiratory allergy has shown a long‐lasting efficacy after its discontinuation, whereas this evidence is still lacking for sublingual immunotherapy, despiteExpand
Randomised controlled trial of local allergoid immunotherapy on allergic inflammation in mite-induced rhinoconjunctivitis
TLDR
The results suggest that this immunotherapy is clinically effective in rhinoconjunctivitis and that it decreases the immune-mediated inflammatory responses to the allergen. Expand
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