• Publications
  • Influence
Structure-activity studies of 16-methoxy-16-methyl prostaglandins.
These studies indicate that the introduction of the methyl and methoxy groups at C-16 into the prostaglandin analogues markedly increases the ratio of antisecretory to diarrheogenic action. Expand
X-ray structure determination of mexiprostil, a new gastroprotective 16-methoxy-16-methyl-PGE1 analogue.
Mexiprostil is a new gastroprotective 16-methoxy-16-methyl-PGE1 methyl ester and X-ray diffraction results established that the configuration at C-15 is also R. Expand
Angiotensin converting enzyme inhibitors as antihypertensive agents: 1-[(2-mercaptocycloalkyl)carbonyl]-L-prolines.
Three of the compounds, namely 1-[[2-(benzoylthio)cyclopentyl]carbonyl]-L-proline, were found to be as potent as captopril in reducing blood pressure and the influence of chirality and ring size on the ACE inhibition is described. Expand
The Paths of Unification In The GUST With The G x G Gauge Groups of E(8) x E(8)
In the framework of the four dimensional heterotic superstring with free fermions we discuss the rank eight and/or sixteen Grand Unified String Theories (GUST) which contain the SU(3)H-gauge familyExpand
Intramolecular 1,3-cycloadditions of nitrile ylides bearing an acetylenic function
Treatment of amides 1a,b with thionyl chloride followed by reaction with triethylamine gave 1,4-dihydro[1]benzopyrano[4,3-b]pyrrole derivatives (4a,b) arising from intramolecular 1,3-cycloaddition ofExpand