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Control of intra- and extra-cellular sulphydryl-disulphide balances with gold phosphine drugs: 31P nuclear magnetic resonance studies of human blood.
It is shown that the monophosphine complex has two binding sites in erythrocytes, probably at the SH groups of glutathione and haemoglobin, and the bis complex solidifies blood via a reductive denaturation of albumin, with the release of OPet3. Expand
Reactions of triethylphosphine gold(I) complexes with heme proteins: novel spin-state changes in cytochrome b562, myoglobin, and hemoglobin.
Two distinct kinetic steps were observed in the autoxidation of HbO2 and MbO2 that may involve the liberation of superoxide and the kinetics of the spin-state change of cyt b562 were too fast to measure by conventional methods. Expand
A 1H nmr study of the interaction of aurothiomalate ("Myocrisin") with human red blood cells in vitro.
The results of 1H spin-echo Fourier transform (SEFT) nuclear magnetic resonance (nmr) experiments suggest that some aurothiomalate binds intracellular glutathione (GSH) when added to suspensions ofExpand
Evaluation of macrophage electrophoretic mobility (MEM) test as an indicator of cellular immunity in ocular tumours.
The macrophage electrophoretic mobility (MEM) test of Field and Caspary did not clearly separate patients with ocular neoplastic disease from those with inflammatory disease, although there was someExpand
The structural flexibility of ferric cytochrome c
In the eukaryotic mitochondrial respiratory chain, cytochrome c transfers electrons from a reductase complex to cytochrome oxidase, the terminal component which reduces molecular oxygen to water.Expand
Complete solubilization of pectins from cotton suspension culture cell walls with retention of most structural features
Cotton suspension culture cell walls contain four major pectin substructures: (1) rhamnogalacturonan I (RGI), (2) rhamnogalacturonan II, (3) highly methyl esterified homogalacturonan, and (4)Expand