Genetics of epidermodysplasia verruciformis: Insights into host defense against papillomaviruses.
- G. Orth
- BiologySeminars in Immunology
- 1 December 2006
Mutations in two adjacent novel genes are associated with epidermodysplasia verruciformis
- N. Ramoz, L. Rueda, B. Bouadjar, L. Montoya, G. Orth, M. Favre
- Biology, MedicineNature Genetics
- 11 November 2002
The identification of nonsense mutations in two adjacent novel genes, EVER1 and EVER2, that are associated with the disease are reported and have features of integral membrane proteins and are localized in the endoplasmic reticulum.
Early regression of cervical lesions in HIV‐seropositive women receiving highly active antiretroviral therapy
- I. Heard, Valérie Schmitz, D. Costagliola, G. Orth, M. Kazatchkine
- MedicineAIDS (London)
- 20 August 1998
It is demonstrated that active antiretroviral therapy may result in a reduced prevalence of cervical squamous intra-epithelial lesions despite the absence of clearance of HPV infection.
Comparative prevalence, incidence and short‐term prognosis of cervical squamous intraepithelial lesions amongst HIV‐positive and HIV‐negative women
- C. Six, I. Heard, I. de Vincenzi
- Medicine, BiologyAIDS (London)
- 18 June 1998
HIV‐induced immunodeficiency is associated with high prevalence, incidence and persistence/progression of squamous intraepithelial lesions (SIL), and HIV‐positive women with SIL may benefit from early treatment when a useful immune response is still present.
Immunization with viruslike particles from cottontail rabbit papillomavirus (CRPV) can protect against experimental CRPV infection
- F. Breitburd, R. Kirnbauer, D. Lowy
- Biology, MedicineJournal of Virology
- 1 June 1995
It is concluded that native VLPs can induce antibody-mediated, type-specific protection against experimental papillomavirus infection against CRPV challenge.
High prevalence of papillomavirus-associated penile intraepithelial neoplasia in sexual partners of women with cervical intraepithelial neoplasia.
- R. Barrasso, J. D. de Brux, O. Croissant, G. Orth
- MedicineNew England Journal of Medicine
- 8 October 1987
The concept that cervical carcinomas and precancerous lesions in women may be associated with genital papillomavirus infection in their male sexual partners is supported.
Severe cutaneous papillomavirus disease after haemopoietic stem-cell transplantation in patients with severe combined immune deficiency caused by common γc cytokine receptor subunit or JAK-3…
- C. Laffort, F. Deist, M. Debré
- Medicine, BiologyThe Lancet
- 19 June 2004
Antibodies to human papillomavirus type 5 are generated in epidermal repair processes.
- M. Favre, S. Majewski, S. Jabłońska
- Biology, MedicineJournal of Investigative Dermatology
- 1 March 2000
The data strongly suggest that extensive keratinocyte proliferation is a major factor for the generation of anti-HPV5 antibodies and that autoimmunity may contribute to this phenomenon.
Bowenoid papulosis of the male and female genitalia: risk of cervical neoplasia.
- S. Obalek, S. Jabłońska, S. Beaudenon, L. Walczak, G. Orth
- MedicineJournal of American Academy of Dermatology
- 1 March 1986
Inherited MST1 Deficiency Underlies Susceptibility to EV-HPV Infections
- Amandine Créquer, C. Picard, E. Jouanguy
- Medicine, BiologyPLoS ONE
- 27 August 2012
The whole-exome based discovery of AR MST1 deficiency in a 19-year-old patient with a T-cell deficiency associated with EV-HPV, bacterial and fungal infections is reported, providing a new genetic etiology of susceptibility to EV- HPV infections.
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