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Thermomechanical behavior of surface acoustic waves in ordered arrays of nanodisks studied by near-infrared pump-probe diffraction experiments
The ultrafast thermal and mechanical dynamics of a two-dimensional lattice of metallic nano-disks has been studied by near infrared pump-probe diffraction measurements, over a temporal range spanningExpand
A biofunctional polymeric coating for microcantilever molecular recognition.
An innovative route to activate silicon microcantilevers (MCs) for label free molecular recognition is presented. The method consists in coating the underivatized MCs with a functional ter-polymerExpand
Nanomechanical recognition of N-methylammonium salts.
Turning molecular recognition into an effective mechanical response is critical for many applications ranging from molecular motors and responsive materials to sensors. Herein, we demonstrate how theExpand
Thermodynamics of mechanical transduction of surface confined receptor/ligand reactions.
Chemomechanics of surface stress is discussed in terms of interfacial thermodynamics. In the first section the paper shows how to quantitatively describe the chemical equilibrium of a receptor/ligandExpand
Role of nanomechanics in canonical and noncanonical pro-angiogenic ligand/VEGF receptor-2 activation.
Vascular endothelial growth factor receptor-2 (VEGFR2) is an endothelial cell receptor that plays a pivotal role in physiologic and pathologic angiogenesis and is a therapeutic target forExpand
Protein thin film machines.
We report the first example of microcantilever beams that are reversibly driven by protein thin film machines fueled by cycling the salt concentration of the surrounding solution. We also show thatExpand
On the thermodynamics of biomolecule surface transformations.
Biological surface science is receiving great and renewed attention owing the rising interest in applications of nanoscience and nanotechnology to biological systems, with horizons that range fromExpand
On the difference of equilibrium constants of DNA hybridization in bulk solution and at the solid‐solution interface
The origin of the difference between the equilibrium (affinity) constants of ligand–receptor binding in bulk solution and at a solid‐solution interface is discussed in terms of Gibbsian interfacialExpand
Molecular recognition by contact angle: proof of concept with DNA hybridization.
A molecular recognition reaction supported by a solid-phase assay drives a specific change in the solid-solution interfacial tension. This prompts contact angle (CA) analysis, being a straightforwardExpand
Advances in parallel screening of drug candidates.
In the hit to lead process, a drug candidate is selected from a set of potential leads by screening its binding with potential targets. This review focuses on the lead identification assays thatExpand