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A comparison of budesonide with prednisolone for active Crohn's disease.
BACKGROUND Patients with active Crohn's disease are often treated with corticosteroids, but the treatment has many side effects. Budesonide is a potent, well-absorbed corticosteroid, but because of aExpand
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Diagnostic Value of Disease History, Clinical Presentation, and Inflammatory Parameters of Appendicitis
The clinical diagnosis of appendicitis needs to be improved, as up to 40% of explorations for suspected appendicitis are unnecessary. The use of body temperature and laboratory examinations asExpand
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Appendectomy and protection against ulcerative colitis.
BACKGROUND A history of appendectomy is rare in patients with ulcerative colitis. This suggests a protective effect of appendectomy or that appendicitis and ulcerative colitis are alternativeExpand
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Natural course of Crohn's disease after ileocolic resection: endoscopically visualised ileal ulcers preceding symptoms.
Forty two Crohn's disease patients were followed up after ileocolic resection with regard to symptoms and endoscopic appearance of the ileocolic anastomosis. Twenty eight patients resected because ofExpand
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Indications for operation in suspected appendicitis and incidence of perforation
Abstract Objective: To clarify poorly understood epidemiological features of appendicitis. Design: Retrospective study of consecutive cases from a defined population and analysis of data fromExpand
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Appendectomy is followed by increased risk of Crohn's disease.
BACKGROUND & AIMS Appendectomy is associated with a low risk of subsequent ulcerative colitis. This study analyzes the risk of Crohn's disease after appendectomy. METHODS We followed-up 212,218Expand
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Different intestinal permeability patterns in relatives and spouses of patients with Crohn’s disease: an inherited defect in mucosal defence?
Background A familial defect in intestinal barrier function has been found in Crohn’s disease. Aim To investigate possible genetic and environmental influences on this barrier defect by studyingExpand
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Mechanism of Absorption Enhancement in Humans After Rectal Administration of Ampicillin in Suppositories Containing Sodium Caprate
AbstractPurpose. The medium chain fatty acid sodium caprate (C10) is approved as an absorption enhancer but its mechanism of action has not been studied in humans. The aim of this study was toExpand
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Thiopurine Therapy Is Associated with Postoperative Intra-Abdominal Septic Complications in Abdominal Surgery for Crohn’s Disease
PURPOSE: Thiopurines are important as maintenance therapy in Crohn’s disease, but there have been concerns whether thiopurines increase the risk for anastomotic complications. The present study wasExpand
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Integrity and metabolism of human ileal mucosa in vitro in the Ussing chamber.
The Ussing chamber is increasingly being used for in vitro studies of human intestinal mucosa, but little attention has been paid to the viability of specimens over time. Ninety-one mucosal specimensExpand
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