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Sleep-disordered breathing and cardiovascular disease: cross-sectional results of the Sleep Heart Health Study.
- E. Shahar, C. Whitney, +7 authors J. Samet
- American journal of respiratory and critical care…
Disordered breathing during sleep is associated with acute, unfavorable effects on cardiovascular physiology, but few studies have examined its postulated association with cardiovascular disease… Expand
Results of a home-based environmental intervention among urban children with asthma.
- W. Morgan, E. Crain, +10 authors H. Mitchell
- The New England journal of medicine
- 9 September 2004
BACKGROUND Children with asthma who live in the inner city are exposed to multiple indoor allergens and environmental tobacco smoke in their homes. Reductions in these triggers of asthma have been… Expand
The Sleep Heart Health Study: design, rationale, and methods.
The Sleep Heart Health Study (SHHS) is a prospective cohort study designed to investigate obstructive sleep apnea (OSA) and other sleep-disordered breathing (SDB) as risk factors for the development… Expand
Prospective Study of Obstructive Sleep Apnea and Incident Coronary Heart Disease and Heart Failure: The Sleep Heart Health Study
Background— Clinic-based observational studies in men have reported that obstructive sleep apnea is associated with an increased incidence of coronary heart disease. The objective of this study was… Expand
Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function
Spirometric measures of lung function are heritable traits that reflect respiratory health and predict morbidity and mortality. We meta-analyzed genome-wide association studies for two clinically… Expand
Sleep-Disordered Breathing and Mortality: A Prospective Cohort Study
In a cohort of 6,441 volunteers followed over an average of 8.2 years, Naresh Punjabi and colleagues find sleep-disordered breathing to be independently associated with mortality and identify… Expand
Epigenetic Signatures of Cigarette Smoking
- R. Joehanes, A. Just, +80 authors S. London
- Biology, Medicine
- Circulation. Cardiovascular genetics
- 1 October 2016
Background—DNA methylation leaves a long-term signature of smoking exposure and is one potential mechanism by which tobacco exposure predisposes to adverse health outcomes, such as cancers,… Expand
The association of sleep-disordered breathing and sleep symptoms with quality of life in the Sleep Heart Health Study.
- C. M. Baldwin, K. Griffith, F. Nieto, G. O'Connor, J. Walsleben, S. Redline
- Medicine, Psychology
- 1 February 2001
This study assessed the extent to which sleep-disordered breathing (SDB), difficulty initiating and maintaining sleep (DIMS), and excessive daytime sleepiness (EDS) were associated with impairment of… Expand
Particle concentrations in inner-city homes of children with asthma: the effect of smoking, cooking, and outdoor pollution.
- L. Wallace, H. Mitchell, +10 authors L. Liu
- Environmental Science, Medicine
- Environmental health perspectives
- 1 July 2003
Inner-city children have high rates of asthma. Exposures to particles, including allergens, may cause or exacerbate asthma symptoms. As part of an epidemiologic study of inner-city children with… Expand
Genome-wide association and large scale follow-up identifies 16 new loci influencing lung function
Pulmonary function measures reflect respiratory health and are used in the diagnosis of chronic obstructive pulmonary disease. We tested genome-wide association with forced expiratory volume in 1… Expand