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- Publications
- Influence
Initiation of biofilm formation in Pseudomonas fluorescens WCS365 proceeds via multiple, convergent signalling pathways: a genetic analysis
- G. O’Toole, R. Kolter
- Biology, Medicine
- Molecular microbiology
- 1 April 1998
Populations of surface‐attached microorganisms comprising either single or multiple species are commonly referred to as biofilms. Using a simple assay for the initiation of biofilm formation (e.g.… Expand
Flagellar and twitching motility are necessary for Pseudomonas aeruginosa biofilm development
- G. O’Toole, R. Kolter
- Biology, Medicine
- Molecular microbiology
- 1 October 1998
The formation of complex bacterial communities known as biofilms begins with the interaction of planktonic cells with a surface in response to appropriate environmental signals. We report the… Expand
Microbial Biofilms: from Ecology to Molecular Genetics
- M. E. Davey, G. O’Toole
- Biology, Medicine
- Microbiology and Molecular Biology Reviews
- 1 December 2000
SUMMARY Biofilms are complex communities of microorganisms attached to surfaces or associated with interfaces. Despite the focus of modern microbiology research on pure culture, planktonic… Expand
Mechanisms of biofilm resistance to antimicrobial agents.
- T. Mah, G. O’Toole
- Biology, Medicine
- Trends in microbiology
- 2001
Biofilms are communities of microorganisms attached to a surface. It has become clear that biofilm-grown cells express properties distinct from planktonic cells, one of which is an increased… Expand
Microtiter dish biofilm formation assay.
- G. O’Toole
- Biology, Medicine
- Journal of visualized experiments : JoVE
- 30 January 2011
Biofilms are communities of microbes attached to surfaces, which can be found in medical, industrial and natural settings. In fact, life in a biofilm probably represents the predominate mode of… Expand
Genetic approaches to study of biofilms.
- G. O’Toole, L. Pratt, P. Watnick, D. Newman, V. B. Weaver, R. Kolter
- Biology, Medicine
- Methods in enzymology
- 1999
Interest in the study of microbial biofilms has increased greatly in recent
years due in large part to the profound impact biofilms have in clinical,
industrial, and natural settings.… Expand
Rhamnolipids modulate swarming motility patterns of Pseudomonas aeruginosa.
- Nicky C. Caiazza, R. Shanks, G. O’Toole
- Biology, Medicine
- Journal of bacteriology
- 1 November 2005
Pseudomonas aeruginosa is capable of twitching, swimming, and swarming motility. The latter form of translocation occurs on semisolid surfaces, requires functional flagella and biosurfactant… Expand
Rhamnolipid surfactant production affects biofilm architecture in Pseudomonas aeruginosa PAO1.
- M. E. Davey, Nicky C. Caiazza, G. O’Toole
- Biology, Medicine
- Journal of bacteriology
- 1 February 2003
In response to certain environmental signals, bacteria will differentiate from an independent free-living mode of growth and take up an interdependent surface-attached existence. These… Expand
Transition from reversible to irreversible attachment during biofilm formation by Pseudomonas fluorescens WCS365 requires an ABC transporter and a large secreted protein
- Shannon M Hinsa, M. Espinosa-Urgel, J. Ramos, G. O’Toole
- Biology, Medicine
- Molecular microbiology
- 1 August 2003
We report the identification of an ATP‐binding cassette (ABC) transporter and an associated large cell‐surface protein that are required for biofilm formation by Pseudomonas fluorescens WCS365. The… Expand
BifA, a cyclic-Di-GMP phosphodiesterase, inversely regulates biofilm formation and swarming motility by Pseudomonas aeruginosa PA14.
- S. Kuchma, Kimberly M. Brothers, J. H. Merritt, N. Liberati, F. Ausubel, G. O’Toole
- Biology, Medicine
- Journal of bacteriology
- 15 November 2007
The intracellular signaling molecule, cyclic-di-GMP (c-di-GMP), has been shown to influence bacterial behaviors, including motility and biofilm formation. We report the identification and… Expand