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An endophytic fungus from Nothapodytes foetida that produces camptothecin.
- S. Puri, V. Verma, T. Amna, G. N. Qazi, M. Spiteller
- BiologyJournal of natural products
- 12 November 2005
Isolation of an organism producing camptothecin and its fermentation may, in the future, provide an easily accessible source for the production of this anticancer drug precursor molecule.
Reactive oxygen species generation and mitochondrial dysfunction in the apoptotic cell death of human myeloid leukemia HL-60 cells by a dietary compound withaferin A with concomitant protection by…
The results of these studies demonstrate that withaferinA induced early ROS generation and mitochondrial dysfunction in cancer cells trigger events responsible for mitochondrial -dependent and -independent apoptosis pathways.
Gluconobacter oxydans: its biotechnological applications.
- A. Gupta, V. Singh, G. N. Qazi, A. Kumar
- Biology, EngineeringJournal of molecular microbiology and…
- 1 July 2001
Its different biotechnological applications, basic biochemistry and molecular biology studies are reviewed and its possible application in biosensor technology has also been worked out.
In vitro antifungal activity of hydroxychavicol isolated from Piper betle L
The antifungal activity exhibited by hydroxychavicol warrants its use as an antIFungal agent particularly for treating topical infections, as well as gargle mouthwash against oral Candida infections.
The endophytic fungus Trametes hirsuta as a novel alternative source of podophyllotoxin and related aryl tetralin lignans.
Piperine, a Phytochemical Potentiator of Ciprofloxacin against Staphylococcus aureus
- I. Khan, Zahid Mehmood Mirza, Ashwani Kumar, V. Verma, G. N. Qazi
- BiologyAntimicrobial Agents and Chemotherapy
- 1 February 2006
The enhanced accumulation and decreased efflux of ethidium bromide in the wild-type and mutant (CIPr-1) strains in the presence of piperine suggest its involvement in the inhibition of bacterial efflux pumps.
The gastric ulcer protective effect of boswellic acids, a leukotriene inhibitor from Boswellia serrata, in rats.
Anticancer activity of an essential oil from Cymbopogon flexuosus.
A standardized root extract of Withania somnifera and its major constituent withanolide-A elicit humoral and cell-mediated immune responses by up regulation of Th1-dominant polarization in BALB/c…
Phytochemical variability in commer- cial herbal products and preparations of Withania somnifera (Ashwagandha)
More than 70-fold variation in the daily intake of withaferin A (the main active constituent of Ashwagandha) was found in the products and emphasizes the need for stringent phytochemical standardization of herbal products.