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B6.C-H-2bm12. A new H-2 mutation in the I region in the mouse
The B6.C-H-2bm12 mutant is described and evidence is presented for the mutational site occurring in the IA subregion. The mutant is of the gain and loss type as bm12 in equilibrium or formed fromExpand
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Murine lymphocyte alloantigens. I. The Ly-6 locus.
The Ly-6 locus and the Ly-6.2 specificity have been previously described, and we now further define this locus and the allelic specificities, Ly-6.1 and Ly-6.2. Back-cross studies and examination ofExpand
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First recognized community outbreak of haemorrhagic colitis due to verotoxin-producing Escherichia coli O 157.H7 in the UK.
The first recognized outbreak of haemorrhagic colitis due to Escherichia coli O 157.H7 in the United Kingdom affected at least 24 persons living in East Anglia over a 2-week period. The illnessesExpand
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Infection with hepatitis B virus after open heart surgery.
Transmission of hepatitis B virus from hospital staff to patients has been described as rare in Britain,' although a more recent review found an average of one outbreak a year between 1975 and 1990.2Expand
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Ir gene function in an I-A subregion mutant B6.C-H-2bm12
The B6.C-H2bm12 (bm 12) strain has a mutation in the I-A subregion of the murine H-2 complex and is characterized by a loss of serologically detected Ia antigens and a strong graft rejection andExpand
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DETECTION OF MOUSE ALLOANTIBODIES BY ROSETTING WITH PROTEIN A‐COATED SHEEP RED BLOOD CELLS
SUMMARY Staphylococcal protein A has an affinity for the Fc portion of the IgG molecule of different species and can therefore be used to detect cell-bound immunoglobulin. Using this property,Expand
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A Phase II Study of Panobinostat with Lenalidomide and Weekly Dexamethasone in Myeloma
Background: Treatment options for multiple myeloma (MM) refractory (ref) to immunomodulatory drugs (IMID) and proteasome inhibitors (PI) are urgently needed. Epigenetic agents e.g. the pan histoneExpand
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Pharmacological antagonism of the toxic manifestations of amitriptyline and protriptyline in dogs.
Abstract In unanesthetized dogs intoxication with amitriptyline produced tachycardia and neurologic changes characterized chiefly by agitation and restlessness. The chronotropic actions of suchExpand
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Murine lymphocyte alloantigens. II. The Ly-7 locus.
The murine Ly-7 locus was identified by the reactivity of alloantisera prepared as B6,C-H-2d x CXBG)F1 anti-CXBK. Most strains, except C57BL/6 and related strains, were Ly-7.2+. Absorption analysisExpand
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IMPLICATION OF THE H‐2L LOCUS IN HYBRID HISTOCOMPATIBILITY (Hh‐1)
The Hh-1 (hybrid histocompatibility) effect in which F1 hybrids with heterozygosity at the “D end” of the H-2 complex can reject parental grafts of the H-2b haplotype was examined in four H-2 mutantsExpand
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