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Troxerutin protects hippocampal neurons against amyloid beta-induced oxidative stress and apoptosis
Alzheimer's disease (AD) is an age-related neurodegenerative disease linked with increased production and/or deposition of amyloid-beta (Aβ) in the brain. The aim of the present study was toExpand
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Post-weaning environmental enrichment improves BDNF response of adult male rats
The environment could have long lasting effects on the individual phenotype through developmental plasticity. Early environmental enrichment exerts profound biological effects, most of which areExpand
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Does ghrelin level change after epileptic seizure in rats?
AIM Epilepsy is one of the most common neurologic problems worldwide. A relationship between epilepsy and hormones has been demonstrated. This study was designed to investigate the effect of seizureExpand
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Inhibition of PTEN protects PC12 cells against oxygen-glucose deprivation induced cell death through mitoprotection
Mitochondria involve in the determination of ischemic neuronal cell fate through regulation of apoptotic and necrotic cell death. Phosphatase and tensin homolog (PTEN) protein negatively regulatesExpand
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Testosterone and Voluntary Exercise Promote Angiogenesis in Hearts of Rats with Diabetes by Enhancing Expression of VEGF-A and SDF-1a.
OBJECTIVES Impaired angiogenesis in cardiac tissue is a major complication of diabetes. This study was aimed to evaluate the effects of testosterone and voluntary exercise on vascular endothelialExpand
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Cardioprotective Effect of Crocin Combined with Voluntary Exercise in Rat: Role of Mir-126 and Mir-210 in Heart Angiogenesis
Background Crocin is reported to have a wide range of biological activities such as cardiovascular protection. Recent epidemiologic studies have shown that exercise reduces cardiovascular morbidityExpand
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Therapeutic effects of 10‐HzPulsed wave lasers in rat depression model: A comparison between near‐infrared and red wavelengths
The application of transcranial low‐level light/laser therapy (tLLLT) in the range of red to near‐infrared (NIR) spectrum for psychological disorders is a new area that is attracting growing interestExpand
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Enduring effects of post-weaning rearing condition on depressive- and anxiety-like behaviors and motor activity in male rats
Environmental manipulation at early critical periods could have long-lasting effects. In spite of the great interest in the biological effects of the environmental condition so far, its long-lastingExpand
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Ghrelin Exerts Analgesic Effects through Modulation of IL-10 and TGF-β Levels in a Rat Model of Inflammatory Pain
Background: Ghrelin is a peptide with attenuating effect on inflammatory pain. Both anti- and pro-inflammatory mediators have a role in the nociception and development of pain and hyperalgesia. IL-10Expand
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Effect of Crocin and Voluntary Exercise on P53 Protein in Pancreas of Type2 Diabetic Rats
Background: Excessive apoptosis of the pancreatic beta-cell has been associated with type 2 diabetes. Hyperglycemia significantly stimulates pancreatic islet cell apoptosis. We evaluated the roleExpand
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