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Pathologic changes of endocrine cells in chronic atrophic gastritis. An ultrastructural study on peroral gastric biopsy specimens.
The endocrine cells seen in metaplastic intestinal epithelium exhibited ultrastruct characteristics of at least three different types of intestinalendocrine cells (EC, L, and S cells).
Argyrophil cell hyperplasia of fundic mucosa in patients with chronic atrophic gastritis.
Argyrophil cell hyperplasia of atrophic fundic mucosa is prevalently found in women with hypergastrinaemia, and the hyperplastic process involves mostly the ECL type of gastric endocrine cells.
Clinical and pathological associations of argyrophil cell hyperplasias of the gastric mucosa.
Hyperplasia of antropyloric argyrophil (non-G) cells was most frequent in patients with gastric peptic ulcer or with hyperplastic polyps as well as in those with atrophic gastritis of the fundic mucosa irrespective of the concomitant condition of antral mucosa.
Gastric carcinoid following gastrojejunostomy
A carcinoid tumor of the gastric body was found in a patient who had a gastrojejunostomy done for duodenal ulcer 36 years earlier, probably related to an elevated gastrin release.
Ultrastructural characterization of fundic endocrine cell hyperplasia associated with atrophic gastritis and hypergastrinaemia
Fundic endocrine cell hyperplasia occurring inhypergastrinaemic CAG is in most cases cytologically similar to that found in other hypergastrinemic conditions, in which the gastrin-dependent ECL cells were already found to prevail, which explains why fundic carcinoids arising in CAG are mostly composed of E CL cells.
Multiple islet cell tumors with predominance of glucagon-producing cells and ulcer disease.
It is concluded that multiple A-cell tumors of the pancreas are an expression of the MEN-I and are mostly associated with ulcer disease and/or with hypergastrinemia of frequent uncertain origin.
Glycoprotein hormone alpha subunit in endocrine cells of human oxyntic mucosa. Studies on its relation to neuroendocrine tumors.
Analysis of similar curves in two other patients with Zollinger-Ellison syndrome, and five patients with hypergastrinemic atrophic gastritis, all presenting alpha-subunit containing oxyntic endocrine cells, showed significant alpha- subunit elevations only in the patients with ulcerogenic syndrome.